Helicobacter pylori(H. pylori)는 만성 위염과 소화성 궤양 등의 원인균으로 잘 알려져 있으며 위암과 mucosa associated lymphoid tissue(MALT)와의 관련성도 체계적으로 밝혀져 있 다. 개발도상국에서 H. pylori는 어려서부터 감염되게 되는데 대 부분의 경우 10세 이전에 감염이 시작된다 1) . 한번 감염되면 수 십 년 지속되는 것이 보통이며 자연 박멸률은 극히 낮다 2) . 한국 인에서의 H. pylori 감염의 혈청학적 역학 연구결과에서 보면, 5 세 미만에 1.1%, 5-10세 사이에 12.8%, 10-15세 사이에 20.4% 인 양성률이 20대에 들어서면 66.7%로 급격히 증가하며 중년기 를 넘어서면 약 60%의 양성률을 보인다. 전체 성인...

BACKGROUND Chronic idiopathic urticaria (CIU) is one of the most frequent skin diseases, however its causes remain unknown in the vast majority of cases. There is increasing evidence for systemic effects of gastric Helicobacter pylori infection, which may result in extra gastrointestinal disorders. Although CIU can result from several causes, a possible relationship between chronic urticaria an...

AIM OF THE STUDY Helicobacter pylori infection plays a crucial role in the pathogenesis of peptic ulcer, and gastric cancer. The current PPI-based triple regimens for the eradication of Helicobacter pylori faces uprising resistance problem demanding for the search of novel candidates. Medicinal plants have always been a source of lead compounds for drug discovery. In the present study, we evalu...

Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children with clarithromycin-resistant ones (P = 0.0001). H. pylori antimicrobial susceptibility is mandatory before choosing a treatment, and clarithromycin should be av...

To model establishment of Helicobacter pylori infection in infants, suckling mice were inoculated with mixtures of strains that preferentially colonize different gastric regions and coexist in vivo. Characterization of H. pylori recovered 2 weeks later showed that susceptibility begins earlier for some strains than for others and that the onset of susceptibility varies among mouse lines.

s on disk. Marathon Multimedia, Northfield, Minn.13. Cammarota, G., G. Fedeli, M. Montalto, et al. 1994. The use of Helicobacterpylori serology in diagnosis and treatment monitoring. In Proceedings of the EHPSG VIIth International Conference.14. Chen, T. S., F. Y. Chang, and S. D. Lee. 1997. Serodiagnosis of Helicobacterpylori infection: comparison and correlation between enzyme...