نتایج جستجو برای: hematopoietic stem cell transplantation

تعداد نتایج: 1898560  

2012
Aysegul Ocal Sahin Miranda Buitenhuis

The formation of blood cells, also called hematopoiesis, is a complex process that occurs in the bone marrow and depends on correct regulation of hematopoietic cell fate decisions. Aberrant regulation of hematopoiesis can result in the development of severe malignant and non-malignant hematological disorders, including leukemia. Hematopoietic stem cell transplantation is the most powerful treat...

Journal: :American journal of respiratory and critical care medicine 2003
Benjamin T Suratt Carlyne D Cool Amanda E Serls Lin Chen Marileila Varella-Garcia Elizabeth J Shpall Kevin K Brown G Scott Worthen

Many of the body's tissues once thought to be only locally regenerative may, in fact, be actively replaced by circulating stem cells after hematopoietic stem cell transplantation. Localization of donor-derived cells ("chimerism") has recently been shown to occur in the lungs of mice after either hematopoietic stem cell transplantation or infusion of cultured marrow. To determine whether tissues...

ژورنال: یافته 2012
انتظامی, کبری , علی مقدم, کامران, شاهسوار, فرهاد ,

Background : Allogeneic hematopoietic stem cells transplantation (HSCT) is a valuable therapy for refractory acute leukemias, leukemias with a high risk for relapse, myelodysplastic syndromes, and chronic myeloid leukemia. HSCT outcome is dependent on several factors, including the stage of disease, degree of human leukocyte antigen (HLA) identity between donor and recipient, conditioning regim...

2014
JAVIER MUNOZ NINA SHAH KATAYOUN REZVANI CHITRA HOSING CATHERINE M. BOLLARD BETUL ORAN AMANDA OLSON UDAY POPAT JEFFREY MOLLDREM IAN K. MCNIECE ELIZABETH J. SHPALL

Allogeneic hematopoietic stem cell transplantation is an important treatment option for fit patients with poor-risk hematological malignancies; nevertheless, the lack of available fully matched donors limits the extent of its use. Umbilical cord blood has emerged as an effective alternate source of hematopoietic stem cell support. Transplantation with cord blood allows for faster availability o...

2017
Aruna V Vanikar Hargovind L Trivedi

[email protected] Abbreviations ABMR: Antibody Mediated Rejections; ADMSC: Adipose Tissue Derived Mesenchymal Stem Cells; AHG: Anti-Human Globulin; ASHI: American Society of Histocompatibility and Immunogenetics; CGN: Chronic Glomerulonephritis; CNI: Calcineurin Inhibitor; CRF: Chronic Renal Failure; DMEM: Dulbecco’s Modified Eagle’s Medium; DSA: Donor Specific Antibody; DST: Donor Specifi...

2017
Wenwen Wang Thomas Stiehl Simon Raffel Van T. Hoang Isabel Hoffmann Laura Poisa-Beiro Borhan R. Saeed Rachel Blume Linda Manta Volker Eckstein Tilmann Bochtler Patrick Wuchter Marieke Essers Anna Jauch Andreas Trumpp Anna Marciniak-Czochra Anthony D. Ho Christoph Lutz

In patients with acute myeloid leukemia and low percentages of aldehyde-dehydrogenase-positive cells, non-leukemic hematopoietic stem cells can be separated from leukemic cells. By relating hematopoietic stem cell frequencies to outcome we detected poor overall- and disease-free survival of patients with low hematopoietic stem cell frequencies. Serial analysis of matched diagnostic and follow-u...

2009
Kathryn Tworkoski

With the growing popularity and acceptability of human embryonic stem cell research, an increasing number of researchers are looking for a way to break into the field and begin utilizing stem cells for their own work. Human Embryonic Stem Cells: The Practical Handbook is an invaluable resource for any such researcher and has plenty to offer experts in the field. The editors have compiled protoc...

Journal: :Haematologica 2012
Fabio Di Giacomo Daniel Lewandowski Eric Cabannes Vanessa Nancy-Portebois Maurice Petitou Serge Fichelson Paul-Henri Romeo

BACKGROUND Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell mobilization is clinically important. DESIGN AND METHODS Heparan sulfate proteoglycans are ubiquitous macromolecules associated with the extra...

2015
Gerhard Hildebrandt

Graft rejection remains a significant concern after hematopoietic stem, cell transplantation (HSCT). While its incidence and predisposing factors are well known in the setting of solid organ transplantation (SOT), the study of graft rejection still remains an area of active investigation in case of HSCT. Recipient T cells, natural killer cells and antibodies are implicated in graft rejection. O...

2015
Soner Solmaz Çiğdem Gereklioğlu Meliha Tan Şenay Demir Mahmut Yeral Aslı Korur Can Boğa Hakan Özdoğu

Thiamine is a water-soluble vitamin. Thiamine deficiency can present as a central nervous system disorder known as Wernicke's encephalopathy, which classically manifests as confusion, ataxia, and ophthalmoplegia. Wernicke's encephalopathy has rarely been reported following hematopoietic stem cell transplantation. Herein, we report Wernicke's encephalopathy in a patient with acute myeloid leukem...

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