Objective To evaluate semen quality in infertile men with a history of unilateral cryptorchidism Methods Semen samples were obtained from 47 infertile men with a history of unilateral cryptorchidism. Semen analysis and membrane integrity including both eosin Y stain and hyo-osmotic swelling tests were performed using standard procedures. All men were divided into three groups according to their...

BACKGROUND AND PURPOSE We sought to determine the frequency of occurrence of contralesional unilateral spatial neglect (USN) after stroke and to investigate the effect of side of lesion, nature of assessment tool used, and timing of assessment relative to stroke onset. METHODS We performed a systematic review of published reports, identified by a search of electronic databases (MEDLINE 1966-1...

At the acute stage following unilateral labyrinthectomy (UL), rats, mice or guinea pigs exhibit a complex motor syndrome combining circling (HSCC lesion) and rolling (utricular lesion). At the chronic stage, they only display circling, because proprioceptive information related to the plane of support substitutes the missing utricular information to control posture in the frontal plane. Circlin...

After vestibular labyrinth injury, behavioral deficits partially recover through the process of vestibular compensation. The present study was performed to improve our understanding of the physiology of the macaque vestibular system in the compensated state (>7 wk) after unilateral labyrinthectomy (UL). Three groups of vestibular nucleus neurons were included: pre-UL control neurons, neurons ip...

Unilateral simian crease (USC) is of the hands. The presence of a single transverse palmar crease or the simian crease (SC) can be seen in normal individuals. The significance abnormal medical conditions. Literature review indicates that presence of a SC and presence of genetic or chromosomal abnormalities in these subset of patients. USC is seen in 10% of the population. In this case report a ...

24 After vestibular labyrinth injury, behavioral measures of vestibular function partially 25 recover through the process of vestibular compensation. The current study was 26 performed to improve our understanding of the physiology of macaque vestibular 27 nucleus neurons in the compensated state (>6 weeks) after unilateral labyrinthectomy 28 (UL). The responses of neurons to sinusoidal yaw rot...

Cerebellar Purkinje cells are excited by two afferent pathways: climbing and mossy fibers. Climbing fibers evoke large "complex spikes" (CSs) that discharge at low frequencies. Mossy fibers synapse on granule cells whose parallel fibers excite Purkinje cells and may contribute to the genesis of "simple spikes" (SSs). Both afferent systems convey vestibular information to folia 9c-10. After maki...

Abstract Background PIK3CA-related overgrowth spectrum (PROS) refers to a group of rare disorders, caused by somatic activating mutations in PIK3CA, resulting abnormal PI3K-AKT-mTOR pathway signalling. Significant associated morbidity is frequently observed, and approved treatments are lacking. Miransertib (ARQ 092) novel, orally available, selective pan-AKT inhibitor with proven vitro efficacy...