Intrinsic involvement of bile ducts, by metastatic colorectal adenocarcinoma growing from within or invading the lumen of bile ducts, is not a well recognized pattern of tumor growth. Clinical, radiographic, operative, and histopathologic aspects of 15 patients with intrabiliary colorectal metastases were described. Fourteen patients were explored for possible hepatic resection. Two had jaundic...

Liver involvement is a common feature of leptospirosis. It is variable from mild to severe hepatic dysfunction. Objective: to analyze liver involvement and to assess its prognostic value in leptospirosis. Materials and methods: We performed analysis of 100 consecutive leptospirosis cases treated in Clinic of Infectious Diseases at University Hospital – Pleven (1976-2015)(90 male, mean age 37±18...

recognition of typhoid hepatitis is important since it has to be differentiated from other common ailments in our country such as viral, malarial or amoebic hepatitis. early institution of specific therapy in cases of typhoid hepatitis carries a good prognosis. in our study, 107 patients with positive blood or bone marrow cultures for salmonella typhi, were evaluated for hepatomegaly and abnorm...

Diffuse involvement of the liver with neoplastic processes can present a diagnostic dilemma. We present the case of a diffusely infiltrative neuroendocrine tumor (NET) that mimicked Budd-Chiari syndrome (BCS), not previously described in the literature. Histological evaluation can be limited without well-defined margins. Only one of two biopsies revealed a NET. A diagnosis of BCS was first cons...

We present the case of a fourteen-year-old girl who complained of depression, weight gain and hirsutism. She was obese, apathetic and had poverty of movements. She had anaemia, deteriorated renal function and elevated hepatic enzymes. Free T3 was <0.19 pg/mL and TSH 276 UI/mL. Antithyroglobulin and antimicrosome antibodies were positive, and the thyroid ultrasonography revealed thyroiditis. She...

Liver involvement in pediatric influenza A (H1N1) infection is rare. Focused clinical evaluation and laboratory tests can rule out or identify hepatic complications early on. Here we report on a 9-year-old boy treated by the Gastroenterology, Hepatology, and Nutrition Unit of Al-Adan Hospital's Pediatric Department. The patient, who was infected with H1N1 during the 2010 pandemic, showed sympto...

OBJECTIVE To identify the prognostic factors of relapse and/or death during the course of primary small-vessel vasculitides (PSVV), and to differentiate their prognostic relevance by the type of vasculitis. METHODS Seventy-five patients were retrospectively followed up after diagnosis: 36 with Wegener's granulomatosis (WG), 23 with Churg-Strauss syndrome (CSS), and 16 with microscopic polyang...

A careful management of hepatic capsular rupture, with massive hemoperitoneum which occurred 14 hours after an emergency cesarean section at 36 weeks of gestation, is meticulously reported. The grade of hepatic involvement varies from minor capsular laceration to extensive parenchymal rupture. Our management involved a combination of surgical interventions and aggressive supportive care. The pa...

Dengue is an acute febrile illness resulting from infection by a flavivirus transmitted by the Aedes mosquito. It is characterized by bleeding manifestations and a plasma leak syndrome. Hepatic involvement in the form of elevation in transaminases is common. However, acute hepatic failure is uncommon. It is not known how the presence of an underlying chronic hepatitis or liver disease affects t...

Hepatic hydrothorax usually presents in association with ascites, but there are rare cases when it does not. This case helps to support the differential of hepatic hydrothorax in patients who have a history of liver cirrhosis, portal hypertension, and recurrent pleural effusions without ascites. We hope to support the conclusion that a patient with recurrent pleural effusions, without ascites, ...