background: in spite of available, and sensitive screening assay for detection of hepatitis b virus surface antigen (hbsag), occasional cases of post-transfusion hepatitis b virus infection are still observed. the aim of the present study was to assess the prevalence of positive anti hepatitis b core (anti-hbc) and presence of hbv-dna in serum sample of healthy blood donors negative for both hb...

Hepatitis B is a global acute and chronic life-threatening liver infection caused by the hepatitis virus. During cadaveric dissection, clinical rotations, autopsy posting, medical students get exposed to patients’ blood body fluids, which increases risk of infection. can be prevented vaccines that are safe, easily available, effective, however many still unvaccinated. This results in need for a...

background and aims: hepatitis d virus (hdv) can infect human population either as a superinfection or concurrent hepatitis b virus (hbv) infection. it is expected that presence of hdv infection is more prevalent in endemic hbv areas. overall 5% of iranian general populations are chronic hbv carriers. the aim of this study was to determine the seroprevalence of hdv and its clinical impact in a ...

Infection with hepatitis B virus can lead to serious long-term complications including chronic hepatitis B virus infection leading to hepatocellular carcinoma, liver failure, and death. We report a case of prolonged hepatitis B antigenemia after routine vaccination with Engerix B. A positive hepatitis B surface antigen was found when the individual donated blood 18 days after vaccination. This ...

Serological markers of hepatitis A and B virus infection were determined by radioimmunoassay in 162 university students. Antibody to hepatitis B e antigen (anti-HBe) was demonstrated in 11 of 15 students positive for both antibody to hepatitis B e antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc). The presence of anti-HBc alone seemed to denote previous hepatitis B virus infec...

Background and Objectives: Vaccination is the major strategy to protect nurses against infection with hepatitis B virus. However, some nurses do not produce sufficient amount of anti-HBsAg antibody required for immunity against infection. Chronic occupational stress has been proposed as a risk factor to humoral immunity. Given that nursing staff is exposed to occupational stress risk, this stud...

objectives in the current case control study, we aimed to compare the histopathological findings of liver to the ccr5δ32 bpdel mutation profiles, expression and some other clinical findings in patients with chronic hcv infection. background the specific antiviral t cells provide cc chemokine receptor 5 (ccr5) for the immune response during the hepatitis c virus (hcv) infection. heterogenous and...

Liver disease has a worldwide distribution.(1,2) Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis and primary hepatocellular carcinoma in most parts of the world. In the developing countries of Asia and Africa, though hepatitis B virus (HBV) infection is the commonest cause of chronic liver disease, HCV is fast evolving as an equally important infection among these popu...

objectives in this study, the association of tgf-β1 +915g/c and -509c/t gene polymorphisms with chronic hepatitis b was evaluated in iranian patients. materials and methods a population-based case–control study was conducted in taleghani hospital, tehran. a number of 220 patients with chronic hepatitis b and the same number of healthy control subjects were designated the case and the control gr...