Effects of acute hypercapnia on the cardiovascular system (CYS) were studied in the anesthetized cat. After surgery the animal was exposed to a gas mixture of 12% CO2 and 25% O2 in nitrogen, and hypercapnia with low levels of arterial pH (pHa) was produced for 20 minutes. In the second run the same level of hypercapnia was induced by ventilating the same cat from the above gas mixture but ...

Ketamine abuse is being increasingly reported worldwide. The drug can produce a dissociative state and hallucinations, making ketamine a favorite recreational agent among drug addicts. Chronic ketamine abuse can damage many organs, including the brain, heart, liver, gastrointestinal tract, and genitourinary system. We report a patient with chronic ketamine abuse who presented with severe cachex...

pancreatitis Active cathepsins B, L, and S in murine and human You might find this additional info useful... abnormal function of the gastrointestinal tract, hepatobiliary system, and pancreas. It is published 12 times a year (monthly) by the publishes original articles pertaining to all aspects of research involving normal or AJP-Gastrointestinal and Liver Physiology

of the human organic solute transporter Protein-protein interactions and membrane localization You might find this additional info useful... published 12 times a year (monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MD involving normal or abnormal function of the gastrointestinal tract, hepatobiliary system, and pancreas. It is publishes original articles pertainin...

OBJECTIVE To assess the feasibility of screening for cholestatic hepatobiliary disease and extrahepatic biliary atresia by using tandem mass spectrometry to measure conjugated bile acids in dried blood spots obtained from newborn infants at 7-10 days of age for the Guthrie test. SETTING Three tertiary referral clinics and regional neonatal screening laboratories. DESIGN Unused blood spots f...

The advent of gadolinium-based "hepatobiliary" contrast agents offers new opportunities for diagnostic magnetic resonance imaging (MRI) and has triggered great interest for innovative imaging approaches to the liver and bile ducts. In this review article we discuss the imaging properties of the two gadolinium-based hepatobiliary contrast agents currently available in the U.S., gadobenate dimegl...

BACKGROUND MRI and perfusion-CT (PCT) are both useful imaging techniques for detection and characterization of liver lesions. The aim of this study was to compare the diagnostic accuracy of imaging parameters derived from PCT and gadoxetic acid-enhanced MRI in patients with hepatocellular carcinoma (HCC). METHODS 36 patients with liver cirrhosis and a total of 67 lesions referred to our hospi...

1 Department of Hepatobiliary Surgery, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu 210008, China 2 Intra-Abdominal Transplant and Hepatobiliary Surgery, Westchester Medical Center of New York Medical College, Valhalla, NY 10595, USA 3Department of Transplantation and Hepatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, S...

Tuberculosis (TB) infection is still common today and remains an important cause of morbidity and mortality. Abdominal TB is one of the most prevalent forms of extrapulmonary manifestations, and collectively refers to gastrointestinal, splenic, pancreatic, hepatobiliary and abdominal lymphadenopathy involvement. The manifestation can be nonspecific, and mimics many conditions, including maligna...