Radiofrequency ablation is one of the most commonly used therapies for potentially curative small hepatocellular carcinoma. Although radiofrequency usually a safe procedure, severe and fatal complications can happen. This case 72 years old woman with cirrhosis secondary to Metabolic Associated Fatty Liver Disease (MAFLD), who presented recurrent hydrothorax after treating carcinoma (HCC) (RFA),...

BACKGROUND Numb is an evolutionary conserved protein that plays critical roles in cell fate determination, cell adhesion, cell migration and a number of signaling pathways, but evidence for a substantial involvement of Numb in HCC has remained unclear. The present study was aimed to investigate the clinical and prognostic significance of Numb and its role in hepatocellular carcinoma (HCC). ME...

Hepatocellular carcinoma (HCC) develops on the background of chronic hepatitis. Leukocytes found within the HCC microenvironment are implicated as regulators of tumour growth. We show that diethylnitrosamine (DEN)-induced murine HCC is attenuated by antibodymediated depletion of hepatic neutrophils, the latter stimulating hepatocellular ROS and telomere DNA damage. We additionally report a prev...

Randomized clinical trials and actual practice differsignificantly. Evidence-based medicine develops new agents referring to, primarily, pharmaceutical findings, preclinical studies and, most importantly, randomized trials. Hepatocellular carcinoma is the common primary malignancy of liver, one main causes fatal outcomes among cancer patients worldwide, including in Asia-Pacific region, with an...

Hepatocellular carcinoma (HCC) is one of the most common cancers, especially in Asia and Africa. The prognosis of HCC is very poor because of the high malignancy and the failure of early diagnosis which is mainly dependent on the late onset of clinical symptoms. Chronic infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is the most commonly known risk factor for developing HC...

Mocanu Elena, University Alley, 900437 Constanta, Romania e-mail: [email protected] ABSTRACT Hepatocellular carcinoma is one of the most common cancers and the age distribution of HCC patients has steadily increased because of the improved management of chronic liver diseases. The peak age of onset of hepatocellular carcinoma is continually increasing worlwide. This study aims to evaluate...

background hepatocellular carcinoma (hcc), a major fatal cancer worldwide, is induced by different etiological factors in the liver. objectives to gain insight into serum protein profiling of hcc with different etiologies. patients and methods we subjected the sera of hbv-hcc, hcv-hcc, non-b non-c-hcc patients, and healthy volunteers to two-dimensional gel electrophoresis (2-de) and liquid chro...

Background: Hepatocellular carcinoma (HCC) is the sixth greatest frequent disease in world and second biggest cause of cancer mortality men developing nations, with over 782,000 deaths globally each year, China accounting for almost half them. Aim study: The goal this research was to see whether epidermal growth factor might be used as an indicator early detection hepatocellular cancer. Patient...