Cantharidin, a potent vesicant and antifeedant agent, is produced by two families of beetles, Meloidae and Oedemeridae (Coleoptera). In this study, the cantharidin content of oedemerid beetles of central Iran was investigated using the GC-MS method. Cantharidin in both sexes of Oedemera podagrariae ventralis Meïneïtrieãs (Oedemeridae) was found in an average of 3.89 µg/beetle in males and 21.68...

BACKGROUND Previous studies showed that shallomin, the active antimicrobial constituent of Persian shallot, has a wide range of antibacterial and antifungal properties. OBJECTIVES The objective of this randomized clinical trial was to evaluate the effectiveness of topical shallomin alcoholic solution in treatment of cold sore. PATIENTS AND METHODS A total of 60 volunteers who met the inclus...

Psychological stress is thought to contribute to reactivation of latent herpes simplex virus (HSV). Although several animal models have been developed in an effort to reproduce different pathogenic aspects of HSV keratitis or labialis, until now, no good animal model existed in which application of a psychological laboratory stressor results in reliable reactivation of the virus. Reported herei...

OBJECTIVE Retrospective study to evaluate the incidence of infectious adverse events in patients with psoriasis treated with etanercept. METHODS Patients with psoriasis or psoriatic arthritis who were treated with etanercept (50 mg, administered weekly via subcutaneous injection) for ≥48 weeks were retrospectively enrolled. Patients were screened for occult infections before treatment commenc...

During a nutrition survey of school children at Pattan in Aurangabad District, my assistant, Dr. S. S. Ahmed, drew my attention to the occurrence, amongst the children, of chronic indurated sores of the skin and deeper tissues, and of shiny depigmented patches indicating scar-tissue of the healed sores. Later the same kind of sore was observed amongst school children at Jalna. Pattan is a town ...