We constructed insertion mutants of herpes simplex virus type 1 that contained a duplication of DNA sequences from the BamHI-L fragment (map units 0.706 to 0.744), which is located in the unique region of the L component (UL) of the herpes simplex virus type 1 genome. The second copy of the BamHI-L sequence was inserted in inverted orientation into the viral thymidine kinase gene (map units 0.3...

Filters with well-defined holes were used to determine the effective diameters in buffer of human immunodeficiency virus type 1, herpes simplex virus type 1, and four bacteriophages (phi X174, T7, PRD1, and phi 6), which may serve as surrogate viruses for testing barrier materials. Bacteriophages phi 6 and PRD1 most closely model human immunodeficiency virus type 1 in filtration size.

purpose: the main purpose of this study was to evaluate the prevalence of herpes simplex virus 1 and 2 (hsv-1 and hsv-2), varicella-zoster virus and adenovirus associated with conjunctivitis in swab samples of patients who referred to eye specialist hospitals in tehran. methods: in this cross-sectional study, swab samples from patients with acute conjunctivitis during the first sixth months of ...

Herpes simplex virus is a leading cause of sporadic encephalitis. While seizures are a common feature of Herpes simplex virus encephalitis, and periods of asystole have been reported in Herpes simplex virus patients, there have been no prior reports of ictal asystole secondary to such an infection.This case report describes a 33 year old, previously healthy, gentleman of Malaysian descent, with...

Introduction: Herpes Simplex Virus type 1 (HSV-1) is the virus that most often infects oral cavity. HSV-1 in latent phase migrates to trigeminal ganglion after primary infection and can reactivate cause recurrent intraoral herpes (RIH). The recurrence of RIH multifactorial triggered by decreased immunity, fatigue, hypersensitivity, stress, ultraviolet. Case: Three male patients came Oral Diseas...

Front Cover. A new C-nucleoside with strongly pairing ethynylmethylpyridone base and 3'-azido-2',3'-dideoxyribose sugar dubbed 'AZW' was described. The image shows the structure of AZW against a backdrop AZT in dotted cloud representation. nucleoside inhibitory activity Herpes simplex virus type 1 (HSV1) as reported by Richert et al. their full paper at10.1002/cbdv.202000937.

INTRODUCTION At the onset of the 20th century, ancient clinical observations of cancer epidemics in Bantu populations of Sub-Saharan Africa were discovered. They were reported from 1914 to 1960, but remained unexplained. In 1983, in San Francisco, Calif., USA, cancer epidemics were related to infections by the human immunodeficiency virus type 1 (HIV-1) known as AIDS disease. Yet since 1996, it...