Currently HIV infection in Kazakhstan is mainly spread among population groups with risk taking behavior (injection drug users - IDUs, sex workers SWs). The lesions and fatalities patients are caused by complications, i.e. the development of opportunistic infections secondary diseases. Timely diagnosis these conditions determines success treatment life expectancy patients. Among superinfections...

Varicella-Zoster virus (VZV) is a human herpesvirus that causes varicella (chickenpox) as primary infection, and, following variable period of ganglionic latency in neurons, it reactivates to cause herpes zoster (shingles). An analysis VZV infection cultures neural cells, particular when these have been obtained from induced pluripotent stem cells (iPSCs) or consisting highly purified neuronal ...

Herpes zoster is a very common viral infection with disabling complications like post herpetic neuralgia in the affected dermatomes. Though this study was aimed to identify most dermatome involved, we also tried find out underlying triggers which herald onset of condition. Adequate treatment at appropriate time will prevent associated disease, thereby enhancing quality life for all patients.

We report four HCV-HIV-coinfected patients who developed herpes zoster or muco-cutaneous herpes virus disease shortly after starting interferon-free antiviral treatment for HCV. We suggest that in our patients the prompt clearance of HCV following direct-acting antivirals leads to a paradoxical effect on the innate and adaptive immune system mediating the reactivation of herpetic infection.

Herpes zoster ophthalmicus commonly presents with vesicular eruptions of skin along a dermatome and post herpetic neuralgia. Viral invasion into the intracranial vessel and resultant arteritis is rare complication, reported mainly in elderly, children and immunocompromised individuals. We report a young immunocompetent male who reported to us with acute right sided hemiparesis following an epis...

Severe acute respiratory syndrome coronavirus (SARS-COV-2) presented with pulmonary symptoms and various extra manifestations including dermatological like urticarial, acralvascular lesion erythematous maculopapular rash, vesicular rash. Herpes zoster is a painful rash resulting from reactivation of varicella-zoster (VZ) virus that also causative agent chickenpox. The incidence HZ infection (HZ...

Herpes zoster and post-herpetic neuralgia deteriorate the quality of life because of severe pain and complications, and cause considerable social and economic burden of disease. In 2012, herpes zoster vaccine was released in Korea. The efficacy of herpes zoster vaccine is known to be 51.3-66.5% among the aged over 60 and 69.8-72.4% among adults between 50 and 59. It is also known that preventiv...

BACKGROUND Herpes zoster is characterized by unilateral grouped vesicles along the distribution of a dermatome. A global recurrence rate as low as 0.5%∼6.2% has been reported for herpes zoster. The recurrence of herpes zoster is higher in immunocompromised patients and older patients. OBJECTIVE The purpose of this study is to assess the frequency of herpes zoster recurrence and factors that c...

Herpes zoster vaccine (Zostavax [Merck & Co., Inc.]) was licensed in 2006 and recommended by the Advisory Committee on Immunization Practices (ACIP) in 2008 for prevention of herpes zoster (shingles) and its complications among adults aged ≥60 years. The Food and Drug Administration (FDA) approved the use of Zostavax in 2011 for adults aged 50 through 59 years based on a large study of safety a...

PURPOSE To examine whether herpes zoster antigen (also called varicella-zoster virus antigen) was detectable in temporal artery biopsies taken from individuals with giant cell arteritis (GCA). DESIGN Retrospective comparative case series. METHODS Sections of formalin-fixed paraffin-embedded temporal arteries were examined first by hematoxylin-eosin (H&E) staining to establish the diagnosis ...