A protocol for testing cerebrospinal fluid specimens using a range of PCR assays for the diagnosis of central nervous system infection was developed and used to test prospectively 383 specimens. PCR assays were used for the detection of adenovirus, Borrelia burgdorferi, enteroviruses, Epstein Barr virus, cytomegalovirus, herpes simplex virus, human herpes virus type 6, JC virus, Leptospira inte...

Introduction Herpes zoster, which can have a major impact on quality of life, results from reactivation of a latent varicella zoster virus (VZV) infection. We hypothesized that giant cell arteritis (GCA) patients are at increased risk of herpes zoster because of treatment with high-dose glucocorticoids and advanced age. Aim of the study, therefore, was to determine cell-mediated and humoral imm...

BACKGROUND A phase 2 trial was conducted to evaluate the efficacy of a topical antiviral, sorivudine, as an adjuvant to valacyclovir for the treatment of acute herpes zoster. METHODS In this randomized, placebo-controlled, double-blind trial, 25 patients were treated with either sorivudine or placebo cream. All patients began 7 days of valacyclovir treatment on day 3. Zoster lesion swab sampl...

Herpes zoster is the consequence of the reactivation of latent varicella-zoster infection. Immunosuppression may be a predisposing factor for herpes zoster. We have retrospectively assessed the risk of herpes zoster, the risk factors for its occurrence, and its evolution in a population of 209 consecutive liver transplant recipients. Herpes zoster developed in 25 (12%) of patients. One-, 3-, 5-...

Varicella-zoster virus is one of six herpesviruses isolated from humans. The core of a typical herpesvirus contains a linear, double-stranded DNA, whereas the viral capsid is icosadeltahedral and contains 162 capsomeres with a hole running down the long axis (1). The varicella-zoster virus (VZV) is associated with two distinct clinical syndromes: varicella (chickenpox) and herpes zoster (shingl...

We report here two cases of laryngitis due to varicella-zoster virus infection. The patients were a 68-year-old male and a 37-year-old male who both presented with pharyngeal pain. A white erosive lesion was noted on hemilateral side of the larynx, but no vocal cord paralysis was observed in either patient. Based on the unilaterality of the lesion, we made a diagnosis of herpes zoster of the la...

Aim: Chronic kidney disease creates a tendency to infections, and infections are the second most common reason for mortality following cardiovascular events in chronic disease. Health authorities recommend vaccination against hepatitis B, annual influenza, pneumonia, zoster, tetanus, new coronavirus people with end-stage Vaccine-preventable diseases cause adult population diseases.
 The pr...

: Varicella zoster virus (VZV) can cause chickenpox (varicella zoster) and shingles (herpes zoster). Herpes affect cranial nerves but rarely impacts the glossopharyngeal nerve (GN) in isolation. We present a literature review examining primary research—published between 2012 2022—reporting herpes affecting GN, while also reporting case of 57-year-old male who presented to his health physician w...

INTRODUCTION Varicella zoster virus is an exclusively human neurotrophic virus. The primary infection with the virus causes varicella. The virus remains latent in nervous tissue and upon secondary activation causes a variety of syndromes involving the central nervous system (CNS) including meningoencephalitis and cerebellitis. MATERIALS AND METHODS In this study, we looked at the epidemiology...

Aim: Herpes zoster is a dermatomal vesicular eruption caused by the reactivation of varicella-zoster virus (VZV) that remains latent in dorsal root ganglia. Due to impairment cellular immune capacity with aging, it commonly seen advanced age. Approximately 3-10% cases need be hospitalized. We aimed determine frequency dissemination and demographic clinical characteristics hospitalized herpes pa...