We report on the development of an uncommon association of pathologic processes, where an invasive adenocarcinoma of the breast developed concomitantly with a primary lymphoma arising in the same breast. The patient, a 78 year old female, presented with two palpable breast lesions in her left breast and an additional lesion in the right breast. Core needle biopsies of the lesions revealed both ...

Objective: To determine concordance and discordance between radiological pathological findings of palpable breast lesions.
 Study Design: Comparative cross-sectional study.
 Place Duration Study: Department Histopathology, Armed Forces Institute Pathology, Rawalpindi Pakistan, from Oct 2018 to Mar 2019.
 Methodology: Imaging histopathologic reports a total 170 female patients wit...

Background/aim: To evaluate the diagnostic performance of strain elastography (SE) combined with B-mode ultrasound in distinguishing between idiopathic granulomatous mastitis (IGM) and malignant breast lesions. Materials and methods: Seventy-seven malignant breast lesions and 36 IGM were assessed using B-mode ultrasound and SE. Ultrasonographic findings for all the breast lesions were classifie...

Introduction Borderline breast epithelial lesions include atypical ductal hyperplasia (ADH), atypical lobular hyperplasia (ALH), and lobular carcinoma in situ (LCIS). These lesions are premalignant and associated with an increased risk of subsequent breast carcinoma in both the ipsilateral and contralateral breast. However, they are inconsistently treated in spite of effective chemoprevention s...

Heterogeneous DNA methylation patterns are linked to tumor growth. In order to study DNA methylation heterogeneity patterns for breast cancer cell lines, we comparatively study four metrics: variance, I (2) statistic, entropy, and methylation state. Using the categorical metric methylation state, we select the two most heterogeneous states to identify genes that directly affect tumor suppressor...

Background and Objectives: Lesions of the thyroid and breast represent the two commonest sources of frozen section in Kuwait. This study investigates the value of intraoperative cytology (IC), preoperative fine needle aspiration cytology (FNAC) and intraoperative frozen section (FS), in improving the diagnostic accuracy of such lesions. Material: Thirty-one breast masses and 45 thyroid lesions ...

Aim: The aim of this study is to study the cytomorphologic features of benign breast lesions and correlate with clinical and histological findings. To find diagnostic accuracy of fine needle aspiration cytology (FNAC) in benign lesions of breast. Methods: Consecutive 100 patients of benign breast lesions which included 94 females and 6 males were subjected to FNAC. Clinical findings including g...

PURPOSE HSP90 chaperones have key client proteins that are involved in all hallmarks of breast cancer growth and progression. The primary aim of this clinical trial was to evaluate the feasibility of using (89)Zr-trastuzumab PET (for HER2-positive breast cancer) or (89)Zr-bevacizumab PET [for estrogen receptor (ER)-positive breast cancer] to determine in vivo degradation of client proteins caus...

PURPOSE To evaluate the efficacy of mammography and sonography together in the assessment of patients with pure invasive lobular carcinomas (ILCs) of the breast. MATERIALS AND METHODS We retrospectively reviewed 38 cases of pure invasive lobular carcinomas of the breast. The tumors were evaluated both mammographically and sonographically. The mammographic images were reviewed by two experienc...