Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women of reproductive age. PCOS typically develops during adolescence and is a heterogeneous syndrome classically characterized by features of anovulation combined with signs of androgen excess (hirsutism, acne). Increasing obesity in adolescents probably exacerbates signs of PCOS, contributing to its earlier recog...

Oculoauriculovertebral spectrum, or Goldenhar Syndrome, is a condition characterized by variable degrees of uni- or bilateral involvement of craniofacial structures, ocular anomalies, and vertebral defects. Its expressivity is variable; therefore, the term "expanded Goldenhar complex" has been coined. The Goldenhar Syndrome usually involves anomalies in craniofacial structures, but it is known ...

Sepsis is one of the leading causes mortality in intensive care units. Its increases, 
 especially with high number comorbidities and immunosuppression. Hemophagocytic syndrome an uncontrolled cytokine storm that develops course increased inflammatory conditions such as sepsis. The clinical picture very wide; because nonspecific symptoms. For this reason; to diagnose hemophagocytic syndrom...

Polycystic ovarian syndrome is the most common endocrine disturbance affecting women, and heterogeneous collection of sign symptoms with a mild some them hard severe disturbances reproductive, metabolic function. To evaluate effectiveness information, education communication regarding polycystic among late adolescent girls .The objective study where to assess existing knowledge in selected coll...

Intestinal pseudo-obstruction is defined as a syndrome in which symptoms and signs of intestinal obstruction occur without evidence for a mechanical obstruction."2 Previous reviews3'4 have highlighted the heterogeneous nature of the syndrome with a wide variety of clinical associations, pathological abnormalities of the smooth muscle or myenteric plexus, and presenting features. The acute syndr...

ix German Abstract — Zusammenfassung xi

Because of Yeneral’s extensive review [2] on atypical hemolytic uremic syndrome (aHUS) published recently in the Turkish Journal of Hematology, I brought it to readers’ attention that more recently some authors do not use ‘aHUS’, which was historically used to distinguish heterogeneous uncharacterized syndromes from Shiga toxin-related HUS, since the term lacks both specificity and suggested ca...

Alveolar hemorrhage (AH) is a heterogeneous clinical syndrome with a high mortality rate that is characterized by extensive bleeding into the alveolar spaces. AH usually develops secondary to immunological disease and, less frequently, to drug use. Presently described is the case of an 86-year-old woman with AH who had been using rivaroxaban for 6 months.

Ectodermal dysplasia includes a large group of syndromes that are clinically and genetically heterogeneous, and are identified by anomalies in structures of ectodermalorigin, and can present with disorders in such structures as hair, nail, teeth, sweat glands, sebaceous glands and conjunctiva and nervous system (Ramesh et al., 2010). This syndrome was first reported by Charles Darwin (1860) (Mi...

Bardet-Biedl syndrome (BBS) is a genetically heterogeneous autosomal recessive disorder characterized by progressive retinal dystrophy, polydactyly, obesity, hypogonadism, mental retardation, and renal dysfunction. Other manifestations include diabetes mellitus, heart disease, hepatic fibrosis, neurological features, and multiple pigmented nevi. To date, twelve BBS genes have been cloned (BBS1-...