this paper analyzes the reaction of the 9th government with workers and capitalists using game theory. the type of game between three players is static with perfect information. strategy of the players is determined through the use of hierarchical processes and network analysis method. the equilibrium between these three players is the nash type of equilibrium. in the hierarchical and network a...

BACKGROUND A hub-and-spoke telestroke network is an effective way to extend quality acute stroke care to remote hospitals and to improve patient outcomes. This study assessed the cost-effectiveness of a telestroke network in the management of acute ischemic stroke from the perspectives of a network, a hub hospital, and a spoke hospital. METHODS AND RESULTS A model was developed to compare cos...

The hub-and-spoke distribution paradigm has been a fundamental principle in geographic network design for more than 40 years. One of the primary advantages that such networks possess is their ability to exploit economies of scale in transportation by aggregating network flows through common sources. In this paper, we consider the problem of designing an optimal hub-and-spoke network in continuo...

In this paper, performance analysis of Shared and Switched Ethernet LANs under Different Scenarios through simulation has been attempted using OPNET as simulating tool. The first scenario was comes under Hub Only scenario. The environment of the network is in an office, which covers an area of 100m X 100m. The hub used is a 16 port hub in an Ethernet environment with the following configuration...

We consider the hub location problem, where p hubs are chosen from a given set of nodes, each nonhub node is connected to exactly one hub and each hub is connected to a central hub. Links are installed on the arcs of the resulting network to route the traffic. The aim is to find the hub locations and the connections to minimize the link installation cost. We propose two formulations and a heuri...

The identification of optimal methylation biomarkers to achieve maximum diagnostic ability remains a challenge. The present study aimed to elucidate the potential molecular mechanisms underlying osteosarcoma (OS) using DNA methylation analysis. Based on the GSE36002 dataset obtained from the Gene Expression Omnibus database, differentially methylated genes were extracted between patients with O...

BACKGROUND AND PURPOSE Telemedicine techniques can be used to address the rural-metropolitan disparity in acute stroke care. The Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) trial reported more accurate decision making for telemedicine consultations compared with telephone-only and that the California-based research network facilitated a high rate of thrombolysi...

one main group of a transportation network is a discrete hub covering problem that seeks to minimize the total transportation cost. this paper presents a multi-product and multi-mode hub covering model, in which the transportation time depends on travelling mode between each pair of hubs. indeed, the nature of products is considered different and hub capacity constraint is also applied. due to ...

The paper provides the upand down-crossing method to study the asymptotic behavior of queue-length and waiting time in closed Jackson-type queueing networks. These queueing networks consist of central node (hub) and k single-server satellite stations. The case of infinite server hub with exponentially distributed service times is considered in the first section to demonstrate the upand down-cro...

In this paper we propose a 4-index formulation for the uncapacitated multiple allocation hub location problem tailored for urban transport and liner shipping network design. This formulation is very tight and most of the tractable instances for MIP solvers are optimally solvable at the root node. While the existing state-of-the-art MIP solvers fail to solve even small size instances of problem,...