The treatment of cancer is an important issue in both developing and developed countries. Clinical use of ultrasound in cancer is not only for the diagnosis but also for the treatment. Focused ultrasound surgery (FUS) is a noninvasive technique. By using the combination of high-intensity focused ultrasound (HIFU) and imaging method, FUS has the potential to ablate tumor lesions precisely. The m...

High-Intensity Focused Ultrasound (HIFU) is an emerging non-invasive surgical technique. HIFU systems are generally designed to deliver a fixed amount of energy to tissue, but because the tissue thermal response is variable across patients and tissue type, this approach can often lead to underdosing or overdosing. In order to improve the dosing precision in HIFU we are investigating real time m...

This work demonstrates the feasibility of using high intensity focused ultrasound (HIFU) for selective ablation of renal tissue through laparoscopic procedures. Two laparoscopic HIFU probe prototypes were developed and tested. Probe 1: It is a hand-held probe with no integrated ultrasound imaging capability. It consists of two focused rectangular HIFU piezoceramic crystals mounted on a stainles...

Introduction In this work, a method for the optimization of volumetric MR-guided high intensity focused ultrasound (HIFU) ablations is presented. While commonly MRguidance of thermal therapies is based on temperature control the on-line assessment of the thermal dose has been suggested to determine the therapy endpoint [1]. Therefore, we propose to monitor the thermal dose [2] of the treated ti...

High Intensity Focused ultrasound (HIFU) is a non-invasive cancer therapy that makes use of the mainly thermal effects of ultrasound to destroy tissue. In order to achieve reliable treatment planning, it is necessary to characterise the ultrasound source (transducer) and to understand how the wave propagates in tissue and the energy deposition in the focal region. This novel exploratory study i...

Background: The rationale was to develop an ablation approach to destroy regions of tumor resistant to radiation and thus reduce the time required for whole tumor ablation, while improving overall tumor control after radiotherapy. Materials and Methods: The system is composed of a micro positron emission tomography (mPET), 7T magnetic resonance imaging (MRI), and a customized MRI-compatible foc...

INTRODUCTION Curative treatments for localized prostate cancer, from least invasive to most invasive, include brachytherapy, cryosurgery, three-dimensional conformal radiation therapy, external beam radiation therapy, and radical prostatectomy. A patient with localized, low risk or intermediate risk prostate cancer who is diagnosed at an early age and receives one of these treatments has only a...

Methods Multiparametric MRI combined with both systematic and fusion biopsy is being utilized more frequently worldwide to select patients for focal therapy. The ability to effectively ablate prostate cancer with transrectal HIFU has been demonstrated by numerous publications to date. Early results from focal HIFU series suggest that side effect profiles such as stricture, erectile dysfunction,...