NMR spectroscopy is a powerful tool for studying the structure, function and dynamics of biological macromolecules. However, non-spectroscopists often find NMR theory daunting and data interpretation nontrivial. As the first of two back-to-back reviews on NMR spectroscopy aimed at non-spectroscopists, the present review first provides an introduction to the basics of macromolecular NMR spectros...

A strong case exists for the introduction of burst non-uniform sampling (NUS) in the direct dimension of NMR spectroscopy experiments. The resulting gaps in the NMR free induction decay can reduce the power demands of long experiments (by switching off broadband decoupling for example) and/or be used to introduce additional pulses (to refocus homonuclear coupling, for example). The final EXtend...

Conventional single-voxel localization for MR spectroscopy (MRS) is restricted to selecting only rectangular-shaped regions of interest (ROIs). The complexity of tissue shapes of interest and the desire to maximize the signal-to-noise ratio (SNR) while minimizing partial-volume effects require more sophisticated localization techniques. A group of spatially selective RF pulses are proposed in t...

The very first steps of condensation as studied experimentally in the simplest molecular system (para-H(2)) are reported. The fast time-space evolution of the nascent clusters have been measured using state-of-the-art Raman spectroscopy implemented on cryogenic supersonic jets. The time-dependent onset of condensation is presented in a non-equilibrium pressure-temperature phase diagram. Dimer a...

We study onset and control of stochastic resonance (SR) phenomenon in two driven bistable systems, mutually coupled and subjected to independent noises, taking into account the influence of both the inertia and the coupling. In the absence of coupling, we found two critical damping parameters: one for the onset of SR and another for which SR is optimum. We then show that in weakly coupled syste...

A fundamental relationship between coherence resonance (CR) and phase synchronization in a self-sustained system in the presence of noise is addressed. A Van der Pol system synchronized by external forcing is taken as an example. It is shown that, in breaking down synchronization, applied noise creates a new ordered motion whose coherence depends resonantly on its intensity, i.e., CR occurs. Th...

background: the purpose of this study is to investigate the relationship between the cognitive impairment and naa/cr and cho/cr ratios in the proton magnetic resonance spectroscopy (1hmrs), and to assess the importance of 1hmrs in the early diagnosis of cognitive impairment in patients with ischemic white matter lesions (wmls). materials and methods: a total of 45 patients (23males and 22 femal...

in this research, the microstructural of low molecular weight 1,2-polybutadiene (1,2-pbd) was conducted by 1h and 13c nuclear magnetic resonance spectroscopy (nmr) to determine the isomeric contents of 1,4-cis, 1,4-trans and 1,2-vinyl in 1,2-pbd polymer structures. number average molecular weight for low molecular weight 1,2-pbd was measured by nmr techniques and the results were compared with ...

microstructural investigation of low molecular weight 1,4-polybutadiene (1,4-pbd) was studied by 1h and 13c nuclear magnetic resonance spectroscopy (nmr). the isomer contents of 1,4-cis, 1,4-trans and 1,2- vinyl in polybutadiene microstructure were determined. the number average molecular weight for low molecular weight polybutadiene was measured by nmr techniques and comparison was made with g...