New 2,4-disubstituted 1,5-benzodiazepine derivatives containing different functional groups have been synthesized and screened for their antibacterial activity. The 2,4-disubstituted 1,5benzodiazepine derivatives were synthesized by reacting substituted chalcones synthesized using aldol condensation with o-phenylenediamine. QSAR studies of synthesized derivatives were performed. QSAR equation s...

We present a new method for recording digital holograms under incoherent illumination. Light is reflected from a 3D object, propagates through a diffractive optical element (DOE), and is recorded by a digital camera. Three holograms are recorded sequentially, each for a different phase factor of the DOE. The three holograms are superposed in the computer, such that the result is a complex-value...

The first part of this work summarises the basic knowledge about holography principles including wave optics and diffraction. The summarised knowledge is consequently exploited in the second part of this work that regards the methods of digital hologram synthesis. The synthesis methods were evaluated and compared and the perspective ones were announced. The perspective synthesis methods served ...

1-[4-(2-Alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones are a novel class of potent cytotoxic agents. These compounds demonstrate low micromolar to submicromolar IC50 values against human Molt 4/C8 and CEM T-lymphocytes and murine leukemia L1210 cells. In this study, a comparative QSAR investigation was performed on a series of 3,5-bis(arylidene)-4-piperidones using different ...

A number of known antifungal pyrrole derivatives and some newly synthesized compounds (5-33) were tested in vitro against Mycobacterium tuberculosis CIP 103471. The majority of tested compounds were efficient antimycobacterial agents showing MIC values ranging from 0.5 to 32 microg/mL. A 3-D-QSAR study has been performed on these pyrrole derivatives to correlate their chemical structures with t...

Inline digital holograms are classically reconstructed using linear operators to model diffraction. It has long been recognized that such reconstruction operators do not invert the hologram formation operator. Classical linear reconstructions yield images with artifacts such as distortions near the field-of-view boundaries or twin images. When objects located at different depths are reconstruct...

The Coupled Wave Theory of Kogelnik has given a wellestablished basis for the comprehension of how light propagates inside a hologram. This theory gives an accurate approximation for the diffraction efficiency of volume phase holograms and volume absorption holograms as well. Mixed holograms (phase and absorption) have been also treated from the point of view of this theory. For instance, Guibe...

A phase-only hologram applies a modal transformation to an optical transverse spatial mode via phase encoding and intensity masking. Accurate control of the optical field crucially depends on the method employed to encode the hologram. In this Letter, we present a method to encode the amplitude and the phase of an optical field into a phase-only hologram, which allows the exact control of spati...

We present a simple yet effective method, without the need for any additional recording of intensity maps or tremendous iterative computations, to recover reference-wave intensity resulting from the complex hologram acquired by quadrature phase-shifting holography. This is achieved by utilizing a certain area of interest in the complex hologram. We select a particular area in the complex hologr...

We propose a novel optical method to display a complex Fresnel hologram using a single spatial light modulator (SLM). The method consists of a standard coherent image processing system with a sinusoidal grating at the Fourier plane. Two or three position-shifted amplitude holograms displayed at the input plane of the processing system can be coupled via the grating and will be precisely overlap...