The complement system has been thought to originate exclusively in the deuterostomes. Here, we show that the central complement components already existed in the primitive protostome lineage. A functional homolog of vertebrate complement 3, CrC3, has been isolated from a 'living fossil', the horseshoe crab (Carcinoscorpius rotundicauda). CrC3 resembles human C3 and shows closest homology to C3 ...

Hydronephrosis is a common finding in urinary tract outflow obstruction. Chronically obstructed hydronephrotic system may be associated with parenchymal changes. Ultrasound, intravenous urography, micturating cysto-urethrogram and scintigraphy are commonly performed to evaluate the cause of obstruction. In childhood, pelviureteric junction obstruction is a common cause of the hydronephrosis. Hy...

Urolithiasis in horseshoe kidney presents a unique challenge in decision-making and technical aspects of calculus treatment. We present our experience with a group of patients with symptomatic calculi in their horseshoe kidneys. We had 8 patients with 9 horseshoe kidneys bearing calculi. They all underwent percutaneous nephrolithotomy. The median size of the calculi was 21 mm (range, 12 to 45 m...

Horseshoe kidney is the most common fusion anomaly of the kidney, with an incidence of approximately 0.25% of the general population.It is more frequently observed in males (M:F 2:1) [1]. Horseshoe kidneys are frequently associated with other congenital anomalies and uretero-pelvic junction obstruction (UPJO) [1]. Horseshoe kidney is a renal fusion anomaly characterized by renal malrotation, va...

Transplantation of the horseshoe kidney can be performed en bloc or split into 2 grafts according to the vascular anomaly and the existence of the urinary collecting system in isthmus. From 2011 to 2014, there were 3 horseshoe kidney transplantations in Korea and transplantations were performed at 2 different centers. The transplantations were carried out successfully for all recipients without...

This image illustrates a horseshoe kidney from an elderly man that was being evaluated for chronic kidney disease associated with diabetes. Horseshoe kidney is the most common renal fusion abnormality, with an incidence of 1/400 worldwide and a male-to-female ratio of 2:1 and is not a cause of impaired kidney function. One theory of the abnormal fusion of the kidneys is that the metanephric bla...

This is a report on a surgery performed in February, 1995 describing the donation of a living donor's horseshoe kidney used for renal transplantation. The recipient was a 31 years-old male on hemodialysis since 1994. The donor was the healthy 55 years-old father of the recipient who had an uncomplicated horseshoe kidney. The isthmus was perfused by an accessory artery. Via transperitoneal appro...

We evaluate the horseshoe drag exerted on a low-mass planet embedded in a gaseous disk, assuming the disk’s flow in the coorbital region to be adiabatic. We restrict this analysis to the case of a planet on a circular orbit, and we assume a steady flow in the corotating frame. We also assume that the corotational flow upstream of the U-turns is unperturbed, so that we discard saturation effects...

BACKGROUND A method for estimating genomic breeding values (GEBV) based on the Horseshoe prior was introduced and used on the analysis of the 16(th) QTLMAS workshop dataset, which resembles three milk production traits. The method was compared with five commonly used methods: Bayes A, Bayes B, Bayes C, Bayesian Lasso and GLUP. METHODS The main difference between the methods is the prior distr...

It is well established that horseshoe crab eggs can develop successfully across a wide range of temperatures and salinities. However, many estuaries in which horseshoe crabs spawn have been heavily impacted by pollutants, and degraded water quality may be affecting the survival of horseshoe crab eggs laid in such areas. Laboratory bioassays using Limulus polyphemus embryos and larvae have shown...