Trajectory prediction (TP) of moving objects has grown rapidly to be a new exciting paradigm. However, existing prediction algorithms mainly employ kinematical models to approximate real world routes and always ignore spatial and temporal distance. In order to overcome the drawbacks of existing TP approaches, this study proposes a new trajectory prediction algorithm, called HDTP (Hotspot Distin...

There has been considerable recent interest in understanding the way in which recombination rates vary over small physical distances, and the extent of recombination hotspots, in various genomes. Here we adapt, apply, and assess the power of recently developed coalescent-based approaches to estimating recombination rates from sequence polymorphism data. We apply full-likelihood estimation to st...

Performance of data forwarding in opportunistic social networks benefits considerably if one canmake use of humanmobility in terms of social contexts. However, it is difficult and time-consuming to calculate the centrality and similarity of nodes by using solutions of traditional social networks analysis, this is mainly because of the transient node contact and the intermittently connected link...

Resolving the time–space (and compositional) evolution of volcanism along long-lived South Atlantic hotspot trails is important to understanding the connection between hotspot volcanism and mantle plumes. Ar=Ar ages are reported here for rocks dredged from a line of five individual seamounts along an 3⁄4290 km northeast to southwest line extending from the vicinity of Saint Helena Island, and a...

OBJECTIVE To investigate the correlation between quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) parameters and microvascular density (MVD) in a human-colon-cancer xenograft mouse model using 3 Tesla MRI. MATERIALS AND METHODS A human-colon-cancer xenograft model was produced by subcutaneously inoculating 1 × 10(6) DLD-1 human-colon-cancer cells into the right hind...

INTRODUCTION Myelodysplastic syndromes encompass a heterogeneous group of clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, refractory cytopenia and a tendency to progress toward acute myeloid leukemia. The accumulation of genetic alterations is closely associated with the progression of myelodysplastic syndromes toward acute myeloid leukemia. OBJECTIVE To i...

The molecular characteristics of the pseudoautosomal region (PAR) of sex chromosomes remain elusive. Despite significant genome-sequencing efforts, the PAR of highly differentiated avian sex chromosomes remains to be identified. Here we use linkage analysis together with whole-genome re-sequencing to uncover the 630-kb PAR of an ecological model species, the collared flycatcher. The PAR contain...

The objective of this chapter is to highlight critical elements affecting the diffusion of broadband wireless Internet at a hotspot location, through a case study. The research deals with a wireless Internet services project in the main Paris airports, and comprises two components. First, we analyze the emergence of a value chain for a new service, based on the cooperation of several firms. In ...

Crime tends to cluster geographically. This has led to the wide usage of hotspot analysis to identify and visualize crime. Accurately identified crime hotspots can greatly benefit the public by creating accurate threat visualizations, more efficiently allocating police resources, and predicting crime. Yet existing mapping methods usually identify hotspots without considering the underlying corr...

charcot-marie-tooth (cmt) is the commonest neurogenetic disorder with phenotypic and genotyping heterogeneity. cmt1a encompasses approximately 60% of all types of cmt and has ad inheritance. cmt1a maps to chromosome17 p11.2 and is majorly caused by 1.5 mb dna duplication that includes the peripheral protein 22 (pmp) genes. the severity, onset and progression of cmt1a vary markedly within and be...