Hub ports play an important role in reducing the number of container routes and saving operating costs liner companies. However, hub failures caused by uncertainties such as natural disasters may cause huge recovery costs. Considering accidental failure probability reallocation feeder ports, a global reliable shipping location problem (RLSHLP) is studied. We use k-means algorithm to divide netw...

PURPOSE The purpose of this study was to use a novel method to quantify the traction applied to the retina during vitrectomy. METHODS Five 20-gauge electric cutters were used. Fresh porcine eyes were positioned in a specially developed holder and transfixed to the retinal layers with a microwire, and the other end was fixed to the load cell of a strain gauge. The cutter to be assessed was int...

An important step in planning the manufacture of a component by CNC machining is the selection of cutting tools. Although it has long been known that the choice of cutter sizes can have a dramatic effect on the overall machining time, few algorithms for optimisation have been available to the production engineer. This paper describes a method for determining a theoretical optimal combination of...

This article presents an analysis of Reception, Staging and Onward Movement hub (RSOM-hub) concept to support Canadian Forces (CF) Northern operations and provides insights into the optimal RSOM-hub locations. RSOM-hubs are permanent or temporary staging bases for cross-loading between strategic and tactical lift during military deployment and sustainment operations. Performance measures were d...

Background Telestroke is recognized as a safe and time-efficient way of treating stroke patients. However, admission centers (spokes) are subject to financial charges which can make them reluctant to join the system. We implemented and assessed an economic model supporting our telestroke system, Virtuall, France, which includes one expert center (hub) and six spokes. Methods The model is base...

Hub location problem (HLP) is one of the most important problems in the areas of logistics and telecommunication network design. In this paper we address the bi-objective non-strict single allocation hub location problem (BONSSAHLP). The non-strict property of this problem which allows establishment of direct links between pairs of non-hub nodes makes it somehow different from the conventional ...

UNLABELLED Hub proteins (those engaged in most physical interactions in a protein interaction network (PIN) have recently gained much research interest due to their essential role in mediating cellular processes and their potential therapeutic value. It is straightforward to identify hubs if the underlying PIN is experimentally determined; however, theoretical hub prediction remains a very chal...