Dried blood spots (DBS) in their current format encounter challenges in bioanalysis using fixed areas, including but not limited to, waste of DBS samples (only a fraction is used for analysis), the need for sample punching leading to concerns of sample carryover, uncertainty for accurate recovery assessments and hematocrit (HCT) effects. Here we describe a novel concept, namely perforated dried...

Great apes are mammals close to humans in their genetic, behavioral, social and evolutionary characteristics and new genomic information is revolutionizing our understanding of evolution in primates. However, all these species are endangered. While there are many global programs to protect these species, the International Union for Conservation of Nature (IUCN) projects that in a near future th...

Mercury (Hg) causes hazardous cumulative effects in humans; like central nervous system disorders,hypertension and chromosomal aberrations. Therefore, due to high toxicity and bioaccumulationfactor, mercury determination and speciation in human blood is very important. A sensitive,accurate, precise and inexpensive method was demonstrated for preconcentration and speciationof ultra-trace mercury...

BACKGROUND The need to understand the contribution of bovine tuberculosis (BTB) to the general tuberculosis burden in a poor resource setting is paramount. The aim of this study is to determine the burden of BTB among herdsmen and cattle in the North Tongu district of Volta Region in Ghana. MATERIALS AND METHODS A cross- sectional study was conducted in the North Tongu District of the Volta R...

Background: Limited information existed on performance tests in Iranian Arab horses. Aims: The objective of this study is to investigate time related changes of cardiac troponin I (cTnI), atrial natriuretic peptide (ANP) and oxidative/antioxidant biomarkers in the serum of Arabian horses before and after regular training. Methods: Blood samples were collected from jugular vein of 25 Arabian hor...

Articles Specs Note From the Edito Foreword Representative Sampling of Human Tissue Technical Considerations for Sampling and Sample Preparation of Biomedical Samples for Trace Element Analysis Environmental Specimen Banking The Selection, Collection, Transport, and Sorage of Biomedical Samples Presampling Factors The Sampling and Analysis of Human Livers The Collection and Preparation of Human...

equine piroplasmosis is a tick-borne disease caused by intra-erythrocyte protozoa, theileria equi and babesia caballi. the present study aimed to detect piroplasm infection in horses in kurdestan province, iran, through molecular and microscopic approaches.n this study, 186 blood samples were randomly collected from horses of five regions of kurdestan province. the tbs-s/tbs-a primer set was us...

BACKGROUND Ehrlichiosis is an emerging tick-borne zoonotic disease caused by the family of Anaplasmatacea. Recently, outbreak of human monocytic ehrlichiosis was reported in northern part of Iran. Besides, serological evidence of canine monocytic ehrlichiosis caused by Ehrlichia canis was reported from southeastern of Iran but the epidemiology of this disease is almost undetermined in Iran. The...