نتایج جستجو برای: human interferon γ
تعداد نتایج: 1748125 فیلتر نتایج به سال:
RATIONALE Unlike conventional dendritic cells, plasmacytoid DCs (PDC) are poor in antigen presentation and critical for type I interferon response. Though proposed to be present in human atherosclerotic lesions, their role in atherosclerosis remains elusive. OBJECTIVE To investigate the role of PDC in atherosclerosis. METHODS AND RESULTS We show that PDC are scarcely present in human athero...
Human neutrophils form extracellular traps during M. tuberculosis infection, but a similar phenomenon has not been reported in human macrophages. Here we demonstrate that M. tuberculosis induces release of extracellular traps from human macrophages. This process is regulated by elastase activity, previously shown to regulate formation of extracellular traps by neutrophils. Interestingly, format...
OBJECTIVE T cells and level of the cytokine interferon-γ (IFN-γ) are increased in adipose tissue in obesity. Hedgehog (Hh) signaling has been shown to potently inhibit white adipocyte differentiation. In light of recent findings in neurons that IFN-γ and Hh signaling cross-talk, we examined their potential interaction in the context of adipogenesis. RESEARCH DESIGN AND METHODS We used Hh repo...
Pleural fluid interferon-γ and tumour necrosis factor-α in tuberculous and rheumatoid pleurisy. T. Söderblom, P. Nyberg, A.-M. Teppo, M. Klockars, H. Riska, T. Pettersson. ©ERS Journals Ltd 1996. ABSTRACT: Tuberculous and rheumatoid pleural effusions show features suggesting a strong local cellular immune response. Pleural fluid (Pf) from patients with tuberculosis, rheumatoid arthritis (RA) an...
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