background: umbilical cord blood (ucb) is an alternative source of hematopoietic stem cell transplantation (hsct), used in leukemia treatment. cd26+ cells, a fraction of cd34 positive cells, are a major population of ucb cells which negatively regulate the in vivo homing and engraftment of hscs. cd26 is highly expressed in various cells such as hscs, immune cells, fibroblasts, and epithelial ce...

background: invasive ductal carcinoma is the most common type of breast cancer in iran. impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood. it is believed that infiltrated immune cells, especially macrophages, may provide help for tumor cell growth and metastasis.   objective: to analyze the status of tumor as...

Background: The immunomodulatory effects of mesenchymal stem cells (MSCs) and their exosomes have been receiving increasing attention. This study investigated the immunoregulatory human amniotic (hAMSCs) on phytohemagglutinin (PHA)-induced peripheral blood mononuclear (PBMCs). Methods: hAMSCs used in experiment were identified by light microscopy flow cytometry, differentiation ab...