نتایج جستجو برای: hyaluronidase
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The concentration and histological distribution of hyaluronan, a tumor promoting extracellular matrix polysaccharide, and the activity of hyaluronidase, a potential source of angiogenic hyaluronan oligosaccharides, were analyzed in malignant epithelial (n 24), borderline (n 8), benign epithelial (n 20), functional cyst (n 21), and normal (n 5) tissue samples of human ovary. Hyaluronan concentra...
It has been demonstrated that solid hepatoma lysosomes lack hyaluronidase activity, whereas normal rat liver lyso somes contain a high level of this enzyme. This result was also found with lysosomes from an ascites hepatoma, Walker carcinoma 256, and virally transformed BHK cells. In contrast, 0-yV-acetylglucosaminidase activity was shown to be present in lysosomes from tumor cells, although it...
We have studied the effect of cold shock on the percentage of enzyme release in buffalo spermatozoa, i.e. alcohol, malic, glucose-6-phosphate, isocitric, lactate, sorbital dehydrogenases, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), hyaluronidase, arylsulphatase A and arylsulphatase B. Significant amounts of alcohol, malic and sorbital dehydrogenases, GOT, hyalu...
The chemical nature of the non-specific hyaluronidase inhibitor normally present in blood serum has not been elucidated, but quinoid and hydroquinoid compounds have been found to be most effective inhibitors of the depolymerization of hyaluronic acid by hyaluronidase in vitro (1, 2). Other researches have suggested that intermediate metabolites of reduced or oxidized quinoid type may appear in ...
Most clinical studies involving rheumatoid factors are made on sera; relatively few investigations are reported on rheumatoid factors in joint fluid, connective tissue extracts, interstitial fluid and cells. Joint fluid of patients with rheumatoid arthritis often contains rheumatoid factor, measured by the latex fixation and sheep cell agglutination tests.,"'8 Mellors, et al.' established evide...
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