نتایج جستجو برای: hybrid mmc
تعداد نتایج: 193763 فیلتر نتایج به سال:
Disposition characteristics of the macromolecular prodrug of mito mycin C (MM< '), mitomycin C-dextran conjugate (MMC-D), in normal and tumor (VX2 carcinoma)-bearing rabbit thigh muscles were studied using the in situ vascular perfusion technique. Three types of cationic MMC-D (MMC-D.,,) and two types of anionic MMC-D (MMC-D.,,) with different carrier molecular weights were used. After bolus ar...
PURPOSE To evaluate ocular straylight before and after photorefractive keratectomy (PRK) for low myopia with and without topical mitomycin (MMC) treatment. METHODS Patients who underwent PRK for low myopia were enrolled into the study. PRK without MMC was performed in 21 eyes (12 patients), whereas PRK with topical 0.02% MMC was performed in 25 eyes (14 patients). Both groups were treated usi...
Composite material is a combination of two or more materials having compositional variations and depicting properties distinctively different from those of the individual materials of the composite. A composite mixture having more than one fiber is known as hybrid composite During the past decade, considerable research effort has been directed towards the development of in situ Metal Matrices h...
In mice and humans, the immunologic effects of developmental exposure to noninherited maternal antigens (NIMAs) are quite variable. This heterogeneity likely reflects differences in the relative levels of NIMA-specific T regulatory (T(R)) versus T effector (T(E)) cells. We hypothesized that maintenance of NIMA-specific T(R) cells in the adult requires continuous exposure to maternal cells and a...
The paper introduces the notion of multimodal cluster (MMC). MMC is a multicomponent spoken unit, which includes diads “meaning + gesture”, “meaning + phonetic phenomenon” (double MMC) or triad “meaning + gesture + phonetic phenomenon” (triple MMC). All components of the same MMC are synchronized in the speech, gestural and phonetic components conveying the same idea as the semantic component (...
With ever-increasing power-density requirements, technologies such as energy storage systems and electric-vehicles can benefit greatly from interfacing medium-voltage (MV)-AC grid like 13.8kV or 30kV using high-AC/low-DC voltage converter. Using modular converter help increase efficiency, while reducing total conversion steps providing flexibility. Full-bridge multilevel converters (FB-MMC) sol...
purpose: to assess alterations in parameters measured by the ocular response analyzer (ora) after photorefractive keratectomy (prk) with or without 0.02% mitomycin c (mmc) in myopic eyes. methods: in 33 right eyes of 33 patients, iop was determined using the goldmann applanation tonometry (gat) before and 3 months after prk. corneal hysteresis (ch), corneal resistance factor (crf), goldmann-cor...
PURPOSE To investigate how mitomycin C (MMC) modulates corneal fibroblast migration and its molecular mechanisms in the wound healing process. METHODS After treatment with 0 and 0.2 mg · mL(-1) MMC for 5 minutes, effect of MMC on cell migration of human corneal fibroblasts (HCFs) was examined with a cell migration assay. Both focal adhesion kinase (FAK) and paxillin (PXN) expressions in HCFs ...
The bioreductive activation of the antitumor quinone mitomycin C (MMC) by NAD(P)H: quinone oxidoreductase 1 (NQO1) is complicated by the ability of MMC to also act as a mechanism-based inhibitor of NQO1 in a pH dependent manner. Inhibition of NQO1 by MMC has been studied in purified enzyme preparations and in cultured cells but has not determined in vivo. In the studies presented here, NQO1 act...
Myelomeningocele (MMC), the most severe form of spina bifida, is a common and devastating malformation. Over two decades of experimental work in animal models have led to the development and clinical application of open fetal surgery for the repair of the MMC defect. This approach offers improved neurofunctional outcomes and is now a clinical option for the management of prenatally diagnosed MM...
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