the current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. among different vehicles, cationic liposomes are frequently used for delivery of genetic material. this investigation aims to prepare and optimize dotap cationic liposomes containing an antisense oligonuclotide (asodn) against protein kinase c alpha in non-small cells lung...

In this article we study the chemical reactions between guanine and two ultimate carcinogens, the 3,4-quinone forms of the estrogens estrone (E1) and estradiol (E2). DNA was truncated to guanine, i.e. no deoxyribose moiety was included. Due to a complex reaction that involves proton transfer via water molecules we applied linear free energy relationships rather than computation of the transitio...

Abstract Biochar is a waste-derived material that can sequester carbon at large scale. The development of low-carbon and sustainable biochar-enhanced construction materials has attracted extensive interest. Biochar, having porous nature highly functionalised surface, provide nucleation sites for chemical reactions exhibit compatibility with cement, asphalt, polymer materials. This study critica...

This article deals with the possibility of partial replacement blast furnace slag (GGBFS) fly ash after denitrification (FAD) in alkali-activated materials. Physical-mechanical and durability properties were tested, hydration reaction was monitored, infrared spectroscopy performed. Results compared between mixtures prepared without (FA), also a mixture based only on GGBFS. The basic result is t...

The hydration of polar and apolar groups can be explained quantitatively, via the random network model of water, in terms of differential distortions in first hydration shell water-water hydrogen bonding angle. This method of analyzing solute induced structural distortions of water is applied to study the ice-binding type III thermal hysteresis protein. The analysis reveals subtle but significa...

The article discusses an effective technology for producing concrete with increased strength. For this purpose, it is proposed to perform preliminary mechanical activation of cement sand natural humidity (5-8%) in energized apparatus, which a rotary-type centrif-ugal mixer-disintegrator. During mixing, hydration occurs the formation nanodis-persed products on surface grains, are stripped off wi...

background: despite almost the three decades passed since the chemical attacks of iraqi’s army against the iranian troops, some veterans are still suffering from long-term complications of sulfur mustard (sm) poisoning, including certain skin complaints specially dryness, burning, and pruritus. we thus aimed to evaluate the skin’s water and lipid content in patients with a disability of >25% du...

this study assesses the kinetics of hydration of pulverised fuel ash and metakaolin cement pastes and compares how the rate of reaction affects the pore-characteristics and resistance to ionic ingress. the degrees of hydration for the different mixtures were evaluated, both as a function of the calcium hydroxide content and with respect to the chemically combined water contents. the reaction ra...

Claud Bernard (1883) postulated that, provided artificial ventilation was performed, it would always be possible to maintain life in a curarized animal, until ultimate reversal of the paralysis had occurred. This presupposed a very low toxicity for the drug and a complete reversibility of its action. Although this belief has been largely justified by both clinical practice (Rizzi, 1955) and ani...

CONTEXT Currently, the literature on hot yoga is lacking, and there is still much to understand regarding the safety of these practices. However, one point of safety often emphasized is hydration during the practice of hot yoga. AIM The aim of this study was to examine hydration encouragement by hot yoga instructors and hydration behaviors and related outcomes by hot yoga participants. METH...