At the University of Rostock, a new electrostimulative total hip revision system is being developed [1]. This system utilizes the accelerating effect of electromagnetic fields on bone regeneration as it has been characterized by Bassett et al. in 1974 [2]. Though this effect is already utilized in several medical applications to enhance bone regeneration after fractures or bone diseases, there ...

OBJECTIVE To fabricate polymeric nanocomposites with excellent photoluminescence, magnetic properties, and stability in aqueous solutions, in order to improve specificity and sensitivity of cellular imaging under a magnetic field. METHODS Fluoridated Ln(3+)-doped HAP (Ln(3+)-HAP) NPs and iron oxides (IOs) can be encapsulated with biocompatible polymers via a modified solvent exaction/evaporat...

Bone is a composite biomaterial mainly composed of packed collagen fibres and nano-sized hydroxylapatite (HA) crystals. Quantitative measurements of bone mine­ ral composition can provide insights into the bone mine­ ral formation in health and disease . Bone mineral characteristics such as crystal lini ty, carbonate and phosphate mineral content may vary as a function of age, sex, diet, bone l...

Literature data on equilibria between solid calcium phosphates having the apatite structure and aqueous solutions containing Na+ and C 032ions were reexamined in view of the present data about the complexation of ions in such systems. Recalculations showed that all solutions were undersaturated or just saturated with respect to either brushite or octocalciumphosphate or more or less finely disp...

Chromatographic analysis of organelle-associated citrate synthase activity revealed distinct mitochondrial and glyoxysomal forms of the enzyme. The chromatographic elution patterns on hydroxylapatite, carboxymethylcellulose and DEAE-cellulose of citrate synthase from the endosperm of 4.5-day-old castor bean seedlings revealed significant differences for mitochondrial and glyoxysomal activities ...

A compound derived from pyruvic acid and homocysteine has been isolated from reaction mixtures containing serinel*C, homocysteine, and serine dehydratase preparations. The formation of this product interferes with commonly used assays of serine dehydratase, which are based on the serine, pyruvic acid, or homocysteine content of incubation mixtures. Improved assay procedures have permitted the i...

An alanine carrier protein was isolated from membranes of the thermophilic bacterium PS3 using ion exchange column chromatography followed by high performance liquid chromatography with a hydroxylapatite column. The final preparation consisted of a single polypeptide, with Mr = 42,500, as estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. A polarity index of 33% was calcula...

The molecular weight of native vaccinia deoxyribonucleic acid (DNA) is 1 to 1.17 times that of native T4 DNA. Sedimentation of denatured vaccinia DNA through alkaline sucrose gradients yields an apparent molecular weight greater than twice that of denatured T4 DNA, implying that the complementary strands of vaccinia DNA do not separate upon denaturation. When alkali-denatured vaccinia DNA is ne...