cuminum cyminum linn. (umbelliferae) is a plant, which has been used as a toothache remedy in folk medicine of iran. in this study, the potential anti-nociceptive and anti-inflammatory activities of the fruit essential oil of c. cyminum has been evaluated in chemical (formalin test) and thermal (tail-flick test) models of nociception and formalin model of acute inflammation in rats and mice. th...

This special issue on the genus Hypericum (family Hypericaceae) consists of 12 articles focusing on recent advancements related to biosynthetic pathways, biotechnology, molecular biology, genomics, pharmacology, and related disciplines. Hypericum is well-known for its medicinal properties. There are about 487 Hypericum spp., which are distributed across every continent except Antarctica. Althou...

BACKGROUND Recent investigations suggest an anti-inflammatory and antibacterial effect of hyperforin, which is a major constituent of Hypericum perforatum L. (Saint John's wort). OBJECTIVE In the present half-side comparison study we assessed the efficacy of a cream containing Hypericum: extract standardised to 1.5% hyperforin (verum) in comparison to the corresponding vehicle (placebo) for t...

St. John's wort (Hypericum perforatum) has been used as a medical herb for over 2000 years. Over the past two decades, its application as a standardized plant extract for treating depression has undergone rigorous scientific investigation, and its effectiveness has been shown in studies comparing it with other commonly used antidepressants and placebos. Safety and tolerability studies have reve...

background: thymus daenensis is on e of the endemic aromatic species in iran that its essential oil is used in food and pharmaceutical industries. objective: in this study, the effects of plant growth stages and distillation methods on essential oil content and thymol percentage of this species were evaluated. methods: the aerial parts of th. daenensis were collected in three stages of plant gr...

Hypericum perforatum L. (St. Johns’ wort) is the most commercially important species of the genus Hypericum and contains a wide range of components including naphthodianthrones, phloroglucinols, tannins, xanthones, phenolic acids and essential oil. In order to establish an efficient protocol for regeneration, the effects of explant type and plant growth regulators on direct and indirect shoot r...

in order to study the response of concentration and composition of essential oil of coriander (coriandrum sativum) to cattle manure and nitrogen fixing bacteria, an experiment was conducted as factorial experiment in the base of randomized complete blocks design with twelve treatments and three replications at homand research station in damavand of iran in 2010. the factors were cattle manure i...

b a ckground: application of plant derivatives have been suggested as alternative sources for mosquito control. m ethods: the root essential oil and methanol extract of c ionura erecta (l.) griseb was tested under laboratory conditions for larvicidal and skin repelleny activities against anopheles stephensi . the chemical compositions of essential oils were analyzed using gas chromatography- ma...

Objectives. There are approximately 400 Hypericum species that grow naturally in different geographic origins of the world. Those species have been used in different folk medicines and screened for their biological activity including cancer. Our country is an important place for Hypericum species which are known as “kantaron, binbirdelik otu, kan otu, kılıç otu, yaraotu, kuzukıran”. We therefor...