Twenty-three children were admitted to a pediatric intensive care unit for scorpion envenomation with severe hypertension. The hypertension responded to analgesics and sedatives in 15 (65 percent) of the 23. The remaining eight children required specific antihypertensive therapy, and their condition promptly responded to intravenous hydralazine and sublingual nifedipine; rebound hypertension wa...

Clobazam, one of the newer benzodiazepines, is now used extensively as first add on therapy in focal epilepsy. A 67-year-old diabetic and hypertensive gentleman with a history frontal contusion year ago, presented clustering seizures. He was started clobazam 20 mg, levetiracetam 1000 mg/day. Recurrence seizures prompted dose escalation to 40 The patient developed hepatic encephalopathy his deco...

Cerebral vessels of the spontaneously hypertensive rat (SHR) are less susceptible to disruption of the blood-brain barrier to proteins during acute hypertension than normotensive controls. This protective adaptation in SHR during acute hypertension is thought to be due to cerebral vascular hypertrophy which leads to increased vascular resistance and attenuation of the increase in cerebral blood...