نتایج جستجو برای: hypogonadotropic hypogonadism

تعداد نتایج: 3749  

Journal: :Journal of Clinical Research in Pediatric Endocrinology 2016

Journal: :Endocrine journal 2014
Masato Kotani Fumihiko Katagiri Tsuyoshi Hirai Jiro Kagawa

The hypothalamic hormone kisspeptin (metastin) regulates human reproduction by modulating gonadotropin-releasing hormone (GnRH) secretion. Kisspeptin is detected in peripheral blood, although GnRH is not. In this study, we measured plasma kisspeptin levels in four male cases with hypogonadism and seven normal male controls using enzyme immunoassay (EIA) to elucidate the clinical implications of...

Journal: :Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2013
E Bolu A Sonmez S Tapan A Taslipinar A Aydogdu C Meric Y Basaran G Uckaya M Serdar I Kurt O Azal

Metabolic disorders and cardiovascular events are increased in hypogonadism. Serum HDL composition is a better cardiovascular predictor than the HDL counts. However, there is no information about the HDL subfractions in patients with hypogonadism. We designed a prospective study to investigate the HDL subfractions in treatment naïve subjects with hypogonadism and the effects of 2 different test...

Journal: :Proceedings of the National Academy of Sciences 2007

Journal: :The Journal of clinical endocrinology and metabolism 2003
Shaun P Brothers Jo Ann Janovick P Michael Conn

In the case of human GnRH receptor (GnRHR) mutants associated with hypogonadotropic hypogonadism, a view emerged that these mutants are correctly routed to the plasma membrane. This view, supported almost entirely by studies using the HA-tag (hemagglutinin influenza virus epitope tag) and other epitope and chimeric tags, obscured recognition that GnRHR mutants frequently become misrouted protei...

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