One of the most common genetic abnormalities, Down syndrome is associated with intellectual disabilities as well as increased incidence of autoimmune diseases. Endocrine disorders, such as diabetes and thyroid dysfunction are amongst the most common. We describe the case of a 27 year old woman diagnosed with diabetes at the age of 9, who had associated crises of loss of consciousness from the a...

introduction: fasting during the holy month of ramadan is an obligation for all adult, healthy muslims. as several studies have indicated, both fasting and energy restriction can alter thyroid hormone metabolism and affect the clinical features and well-being of hypothyroid patients. hypothyroidism is more prevalent among women and the elderly. its prevalence has been reported to be 4-8% of the...

BACKGROUND We report the prevalence of coronary artery disease (CAD) associated with subclinical hypothyroidism in older persons. METHODS We investigated the prevalence of subclinical hypothyroidism and its association with dyslipidemia and with CAD in 170 women and 110 men, mean age 75 +/- 9 years, in an academic nursing home. RESULTS Of 280 persons, 18 (6%) had subclinical hypothyroidism,...

conclusions we revealed that thyroid dysfunction during pregnancy was associated with iugr and low apgar score even in subclinical forms. further studies are required to determine whether early diagnosis and treatment of thyroid diseases, even in subclinical form, can prevent their adverse effect on fetus. background maternal thyroid function alters during pregnancy. inadequate adaptation to th...

abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

Objectives: To compare BMI and inverted BMI in evaluating body measurement, resting blood pressure, Dual energy X-ray absorptiometry (DEXA) parameters of fat mass and metabolic risk factors in Iranian children Materials and Methods: This is a cross-sectional study on 477 children aged 9-18 yearsin the South of Iran. Weight, height, resting blood pressure, waist and hip circumference and puberta...

Introduction: Congenital hypothyroidism is the most common cause of preventable mental retardation in children. However, early diagnosis and treatment improve the prognosis of mental retardation. Clinical diagnosis of Congenital hypothyroidism is not also evident in the neonatal period. Therefore, screening all newborns for early diagnosis and treatment is essential. This paper aimed to analyze...

Background Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases in childhood and is frequently associated with growth retardation. Vitamin D is critical to bone mineral metabolism and to the growth and development of the skeleton. We aimed to...

background : type 1 diabetes mellitus is the most common endocrine disease in pediatric. we aimed to determine the demographic characteristics at presentation of childhood type 1 diabetes mellitus in hamadan, west province of iran. methods : in this cross sectional descriptive study, demographic data of children with type 1 diabetes mellitus being followed up in pediatric endocrinology clinic o...