نتایج جستجو برای: i proviral load

تعداد نتایج: 1179817  

Journal: :Blood 1994
S Takemoto M Matsuoka K Yamaguchi K Takatsuki

Adult T-cell leukemia (ATL) is neoplasm of the mature helper T lymphocytes and human T-cell lymphotropic virus type-I (HTLV-I) has been shown to be causative virus of ATL. Because HTLV-I integrates its provirus randomly into host chromosomal DNA, monoclonal integration of HTLV-I provirus indicates the clonal proliferation of HTLV-I-infected cells. Therefore, demonstration of clonality of HTLV-I...

Journal: :Genetical research 1995
S J Kay P D Keightley

A high frequency of proviral acquisition has previously been reported in the offspring of SWR/J-RF/J hybrid mice. In the present study, it was investigated whether this proviral acquisition would be useful for large-scale insertional mutagenesis studies. A population of SWR/J-RF/J hybrid mice with a predominantly SWR/J background was created. Lines of mice with such a background and partially c...

Journal: :Technical reports of the Australian Museum 2023

Koala retrovirus (KoRV) infection, endogenous in all northern koalas (Phascolarctos cinereus), has been found to occur at lower, but increasing, prevalence the Kangaroo Island and Mount Lofty Ranges koala populations South Australia. Proviral viral loads are also lower than Queensland koalas, which may be due exogenous spread of or related variable presence genes fragmented expression that posi...

2017
Miriam Rosás-Umbert Beatriz Mothe Marc Noguera-Julian Rocío Bellido Maria C Puertas Jorge Carrillo C Rodriguez Núria Perez-Alvarez Patricia Cobarsí Carmen E Gomez Mariano Esteban Jose Luis Jímenez Felipe García Julià Blanco Javier Martinez-Picado Roger Paredes Christian Brander

The most relevant endpoint in therapeutic HIV vaccination is the assessment of time to viral rebound or duration of sustained control of low-level viremia upon cART treatment cessation. Structured treatment interruptions (STI) are however not without risk to the patient and reliable predictors of viral rebound/control after therapeutic HIV-1 vaccination are urgently needed to ensure patient saf...

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