Dear Editor, We read with great interest the recently published article entitled “Verum versus sham manual acupuncture for migraine: a systematic review of randomised controlled trials” by Yang et al. The authors examined the efficacy of verum acupuncture compared with sham acupuncture for the treatment of migraine. However, in our opinion, they should have exercised more caution when drawing c...

BACKGROUND Treatment of patients with attention deficit hyperactivity disorder (ADHD) with homeopathy is difficult. The Swiss randomised, placebo controlled, cross-over trial in ADHD patients (Swiss ADHD trial) was designed with an open-label screening phase prior to the randomised controlled phase. During the screening phase, the response of each child to successive homeopathic medications was...

A randomized, double-blind, placebo-controlled, parallel-group clinical study with an extra non-treatment group was performed to measure the effect of a single dose of standardized SHR-5 Rhodiola rosea extract on capacity for mental work against a background of fatigue and stress. An additional objective was to investigate a possible difference between two doses, one dose being chosen as the st...

OBJECTIVE Whole-body vibration can be used to supplement canonical physical treatment. It is performed while probands stand on a vibrating platform. Therapeutic vibration can be generated as a stochastic vibratory pattern, referred to as stochastic resonance whole-body vibration (SR-WBV). Despite the widespread use of SR-WBV its neurophysiological mechanism is unclear. DESIGN A randomized sha...

We investigated the second language (L2) acquisition of pragmatic categories that are not as consistently and frequently encoded in the L2 than in the first language (L1). Experiment 1 showed that Italian speakers linguistically highlighted affirmative polarity contrast (e.g. The child ate the candies following after The child did not eat the candies) in 34.3% of the cases, by producing a nucle...

BACKGROUND Here we investigate the effect of millicurrent treatment on human chondrocytes cultivated in a collagen gel matrix and on human osteochondral explants. METHODS Human chondrocytes from osteoarthritic knee joints were enzymatically released and transferred into a collagen type-I gel. Osteochondral explants and cell-seeded gel samples were cultivated in-vitro for three weeks. Samples ...

Coumarin as an additive or as a constituent of tonka beans or tonka extracts is banned from food in the United States due to its potentially adverse side effects. However, coumarin in food from other natural ingredients is not regulated. "True Cinnamon" refers to the dried inner bark of Cinnamomum verum. Other cinnamon species, C. cassia, C. loureiroi, and C. burmannii, commonly known as cassia...

BACKGROUND Mortality in patients with severe sepsis remains high despite the development of several therapeutic strategies. The aim of this randomized, double-blind, placebo-controlled trial was to evaluate whether homeopathy is able to influence long-term outcome in critically ill patients suffering from severe sepsis. METHODS Seventy patients with severe sepsis received homeopathic treatmen...