This patient has cranial diabetes insipidus and hypoparathyroidism with low serum testosterone level and normal range FSH and LH. There was no evidence of granulomatous diseases, histiocytosis or sarcoidosis despite a history ofpolyuria for more than 10 years, although these may take years to manifest2 and diabetes insipidus may be an early manifestation. However, as has been reported,' about 3...

To investigate hypothalamic-pituitary functions and the primary site of the lesion in idiopathic pituitary dwarfism, various pituitary function tests, especially the pituitary hormone responses to the hypophysiotropic hormones were studied in 23 patients with idiopathic pituitary dwarfism. A few cases showed slight responses of GH to GH stimulation tests. Gonadotropin deficiencies were most fre...

BACKGROUND Amenorrhea is a common adverse effect of treatment with antipsychotic medications that influences both fertility and adherence to medication regimens. Most research suggests that medication-induced prolactinemia is the main cause of amenorrhea but few prospective studies have assessed this hypothesis. AIM Identify risk factors for amenorrhea following treatment with antipsychotic m...

One of the symptoms of anorexia nervosa (a.n.) is cessation of pubescence or secondary amenorrhea. Their origin in anorexia nervosa is multifactorial, partly resulting from starvation-induced hipogonadism. Amenorrhea in a.n. may persist despite weight recovery and is often related to osteoporosis. The authors' present causes of amenorrhea and its persisting in a.n., pointing to the factors infl...

Central precocious puberty (CPP) is due to the premature activation of hypothalamic–pituitary–gonadal axis, which responsible for appearance secondary sexual characteristics. It occurs before age 8 and 9 in girls boys, respectively. CPP shows higher incidence females than males. Causes are similar both sexes, but idiopathic form more frequent girls, while organic forms Recent studies demonstrat...

The majority of male infertility is idiopathic. However, there are multiple known causes of male infertility, and some of these causes can be treated medically with high success rates. In cases of idiopathic or genetic causes of male infertility, medical management is typically empirical; in most instances medical therapy represents off-label use that is not specifically approved by the FDA. Un...

Growth without growth hormone (GH) has occasionally been described in patients with organic pituitary pathology, and even more rarely in patients with idiopathic pituitary hormone deficiency. The mechanism of growth without GH remains a mystery. We describe a 17-year old male who grew 38.5 cm in height over a 7-year period, despite the fact that he had established panhypopituitarism. The hypopi...

A 38-year-old man presented with headache, fever, and double vision associated with right abducens nerve paresis. He had neither nuchal rigidity nor visual field defect. Laboratory data revealed elevated erythrocyte sedimentation rate (ESR), eosinophilia, and lymphocytic pleocytosis in the cerebrospinal fluid (CSF). Provocation tests of pituitary hormones showed partial hypopituitarism. Magneti...

amenorrhea, an absence of menses is a symptom that generally brings teenagers for evaluation. this study was undertaken to determine the etiology of primary amenorrhea with especial concern to non classic congential adrenal hyperplasia (nc-cah)-due 21 hydroxylase deficiency among female adolescents refered to clinics of pediatric endocrinology of tehran and iran university of medical sciences a...

BACKGROUND In 1992, the concept of female athlete triad was introduced to describe the interrelated problems of amenorrhea, eating disorders and osteoporosis seen in female athletes. To gain a clearer picture of amenorrhea/oligomenorrhea in Iran, one of the main components of the female athlete triad, we therefore established this study on the prevalence of amenorrhea/oligomenorrhea in elite Ir...