Background: Despite the use of prostate specific antigen (PSA), Gleason-score, and T-category as prognostic factors, up to 40% of patients with intermediate-risk prostate cancer will fail radical prostatectomy or precision image-guided radiotherapy (IGRT). Additional genetic prognosticators are needed to triage these patients toward intensified combination therapy with novel targeted therapeuti...

Cone Beam Computed Tomography (CBCT) is an imaging modality that has been used in image-guided radiation therapy (IGRT). For applications such as lung radiation therapy, CBCT images are greatly affected by the motion artefacts. This is mainly due to low temporal resolution of CBCT. Recently, a dual modality of Electrical Impedance Tomography (EIT) and CBCT has been proposed, in which the high t...

BACKGROUND AND STUDY AIMS Endoscopic ultrasound (EUS)-guided fiducial marker placement for image-guided radiation treatment (IGRT) is becoming more widespread. Most case series report the procedure performed using fluoroscopy for spatial geometry although the benefits of this are unclear. The aim of our study is to report the technical feasibility, safety, and migration rate of fiducial marker ...

Article history: Received 1 March 2016 Accepted 1 March 2016 Available online 4 March 2016 the precision of radiotherapy delivery (e.g. computational algorithms, IMRT, IGRT, SBRT); and3. Incorporationof novel radiosensitizing andmolecular targeting agents with radiation therapy to reduce mechanisms of radiation resistance (e.g. epithelial growth factor receptor inhibitors and RT in head and nec...

The utility of a novel, high-precision, non-intrusive, wireless, accelerometer-based patient orientation monitoring system (APOMS) in determining orientation change in patients undergoing radiation treatment is reported here. Using this system a small wireless accelerometer sensor is placed on a patient's skin, broadcasting its orientation to the receiving station connected to a PC in the contr...

Ths paper examines several applications of deformable registration algorithms in the field of image-guided radiotherapy. The first part focuses on the description of input and output of deformable registration algorithms, with a brief review of conventional and most current methods. The typical applications of deformable registration are then reviewed on the basis of four practical examples. Th...

Dear Editor, Over the last few years, medical LINAC manufacturers have started to offer couch tops or inserts designed for image-guided radiation therapy (IGRT). These couch tops have a homogeneous construction, with a carbon fiber shell and no metal components. Although the use of these couches may offer some advantages in image quality, it can have a potentially serious impact on skin sparing...

The advent of kilovoltage cone-beam computed tomography (CBCT) integrated with a linear accelerator allows for more accurate image-guided radiotherapy (IGRT). The IGRT technique corrects target displacement based on internal body information obtained by acquiring the CBCT image set and registering it with the simulation CT image set just before the beam is delivered. In the present paper, we co...

Eu- and Li-doped yttrium oxide nanocrystals [Y2-xO3; Eux, Liy], in which Eu and Li dopant ion concentrations were systematically varied, were developed and characterized (TEM, XRD, Raman spectroscopic, UV-excited lifetime, and ICP-AES data) in order to define the most emissive compositions under specific X-ray excitation conditions. These optimized [Y2-xO3; Eux, Liy] compositions display scinti...