34 IMMUNE RESPONSES TO MICROBES Two important vaccine advances have been the development of nanoparticle-based vaccine formulations and the identification of unique microbial products that are agonists for immunologic receptors: virus-like particles (VLPs) or nanoparticles, and Toll-Like Receptor (TLR) agonists, respectively.1-3 The immune system continuously screens for and interacts with micr...

Imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. Interleukin-10(IL-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. Therefore, alteration in expression of IL-10 during pregnancy may result in several pathologic conditions such as preterm labor. IL-10 leads to a normal pregna...

This experiment was conducted to examine the effect of multi-strain probiotic (Primalac) on performance, immune responses and cecal microflora in broiler chickens under cyclic heat stress condition. A total of 96 one-d-old mixed sex broiler chicks (Ross 308) were weighed and randomly allocated to two treatment groups, each with 4 replicate pens of 12 chicks. The dietary treatments were basal di...

Background: Vaccines capable of controlling tumor virus based infections are found difficult to develop due to the consistence latent infection in the host. DNA vaccines are attractive tools for the development of HPV vaccines and inducing antigen-specific immunity owing to the stability, simplicity of delivery, safety and cost effectiveness. However, there is a need to increase their potency b...