Fucoidan, a sulfated polysaccharide contained in brown algae, has a variety of immunomodulatory effects, including antitumor and antiviral effects. On the other hand, lactic acid bacteria (LAB) also have immunomodulatory effects such as anti-allergic effects. In this study, we demonstrated that fucoidan enhances the probiotic effects of LAB on immune functions. By using Peyer's patch cells and ...

the present study was undertaken to investigate immunomodulatory activity of Clitoria ternatea seed and root extracts. Effects on humoral immune response were investigated in SRBCs-sensitized rats. Effects on cell medicated immunity were studied by measuring delayed type hypersensitivity (DTH) response in SRBC-sensitized rats. Neutrophil recruiting and phagocytosis were measured by studying neu...

Neolitsea species, medicinal plants belonging to Lauraceae, contain rich alkaloids, steroids, sesquiterpenoids, and triterpenoids which possess antimicrobial, antioxidant, and anti-inflammatory bioactivities. However, species differences in the immunomodulatory effects and evidence pertaining to the effects of Neolitsea species on adaptive immunity are scarce. This study aimed to evaluate the i...

objective: vernonia amygdalina (v.  amygdalina) leaf is locally employed in the southern region of nigeria in the treatment of malari a infection. this study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of v.  amygdalina leaf. materials and methods: the active principles of the dried leaf were extracted with ethanol. for quality validation, ch...

nephrotoxicity is a major side effect of cisplatin, a widely used chemotherapy agent. morphine and other opioids are also used extensively in different types of cancer for the clinical management of pain associated with local or metastatic neoplastic lesions. in addition to its analgesic effects, morphine has also been reported to possess potential immunomodulatory and antioxidant properties. h...

objective(s):gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. in this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. materials and methods: three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (ip) for the evaluation o...

Macrolide antibiotics, a class of potent antimicrobials, also possess immunomodulatory/anti-inflammatory properties. These properties are considered fundamental for the efficacy of macrolide antibiotics in the treatment of diffuse panbronchiolitis and cystic fibrosis. In patients with asthma, macrolide antibiotics have been reported to reduce airway hyperresponsiveness and improve pulmonary fun...

Pediatric uveitis may be a serious health problem because of the lifetime burden of vision loss due to severe complications if the problem is not adequately treated. Juvenile idiopathic arthritis (JIA)-associated uveitis is characterized by insidious onset and potentially blinding chronic anterior uveitis. Periodic ophthalmologic screening is of utmost importance for early diagnosis of uveitis....