نتایج جستجو برای: immunosuppressants
تعداد نتایج: 1972 فیلتر نتایج به سال:
OBJECTIVE Anti-synthetase syndrome (anti-SS) is frequently associated with myositis and interstitial lung disease (ILD). We evaluated prospectively, in a multicenter, open-label, phase II study, the efficacy of rituximab on muscle and lung outcomes. METHODS Patients were enrolled if they were refractory to conventional treatments (prednisone and at least 2 immunosuppressants). They received 1...
INTRODUCTION Despite diagnostic and therapeutic advances, infective endocarditis (IE) remains a challenging and potentially lethal disease. The prognosis of IE remains poor; in the last 30 years, its incidence and mortality have only been marginally reduced. Early identification of high-risk patients can change the course of the disease and improve outcomes. OBJECTIVES AND METHODS To describe...
The control of immune-mediated transplant rejection by immunosuppressive agents might affect other human cells’ proliferation and function. This study aims to evaluate the effect of three immunosuppressants on the proliferation of human adipose-derived adult stroma (ADAS) and human umbilical vein endothelial cells (HUVEC). These cells were used as a culture model to study the minimum inhibitory...
T ransplantation is the accepted treatment of end-stage organ failure. The introduction of cyclosporine (CsA) in the early 1980s greatly improved the outcome of solid organ transplantation, with an increase in 3-year survival from almost 40% to 70%. Substantial advances in the development of additional immunosuppressants have allowed transplant physicians to more specifically modulate the immun...

 Four systematic reviews, 1 randomized controlled trial (RCT), economic evaluation, and 2 evidence-based guidelines were identified.
 reviews (2 that included moderate- to high-quality evidence did not report the quality of evidence) RCT (that provided reported on clinical effectiveness rituximab (RTX) for treatment neuromyelitis optica spectrum disorder (NMOSD). Overall, RTX appeare...
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