نتایج جستجو برای: immunosuppressive effect
تعداد نتایج: 1659768 فیلتر نتایج به سال:
Serum lactate levels are traditionally interpreted as a marker of tissue hypoxia and often used clinically as an indicator of severity and outcome of sepsis/septic shock. Interestingly, recent studies involving the effects of tumor-derived lactate suggest that lactate itself may have an immunosuppressive effect in its local environment. This finding adds to the recent advances in immunometaboli...
Background and Aim: Pemphigus is one of the most common types of autoimmune blistering disease that requires systemic immunosuppressive therapy. Immunosuppressive therapy has improved the disease outcome in recent decades, but long-term use of them has side effects. Recently, it has been tried to evaluate immunosuppressive drugs with less side effects. One of them is mycophenolate mofetil. The ...
Introduction: Concomitant therapy with antiresorptive/antiangiogenic drugs is common in cancer management and reported to have a modifying effect on MRONJ development. M-TOR inhibitors antiangiogenic immunosuppressive properties.Case report: A case of 62 years old female history who developed recurrent mandibular osteonecrosis following few administration sole Everolimus here.
Invasive extramammary Paget's disease (EMPD) is relatively rare and is reported to be highly metastatic to lymph nodes or even other organs, including bone. Histologically, EMPD shows significant numbers of lymphocytes around the tumor mass, suggesting the possible development of novel immunomodulatory therapy for EMPD by targeting these infiltrating lymphocytes. Previously, bisphosphonates (BP...
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