Environmental variations in patient-dependent and surgical factors were modeled using robust optimization with a finite element acetabular cup-pelvis model. A previously developed statistical optimization scheme was used to: (1) determine the cup geometry and the optimal cup-bone interference that maximized bone-implant contact areas and minimized changes in the gap volume between the implant a...

This study analyzes the heat transfer in human eyes following implantation of retinal prostheses using an axisymmetric formulation of the Finite Volume Method. The model used consisted of a vertex centered unstructured grid finite volume method in an edgebased data structure and an explicit time integration. The results of the finite volume thermal analysis in ocular tissues were determined in ...

Advances in imaging technology and computer-assisted design (CAD) have recently enabled the introduction of patient-specific knee implant designs that hold the potential to improve functional performance on the basis of patient-specific geometries, namely a patient-specific sagittal and coronal curvature, as well as enhanced bone preservation. The objective of this study was to investigate the ...

PURPOSE The purpose of this article is to describe a new technique and the anatomic sites for cutting and harvesting bone for grafting applications. A handheld instrument is described that cuts and collects thin shavings of bone from cortical surfaces. MATERIALS AND METHODS This study included 193 consecutive patients who needed bone augmentation and simultaneous implant placement in the seve...

Total ankle replacement remains a less satisfactory solution compared to other joint replacements. The goal of this study was to develop and validate a finite element model of total ankle replacement, for future testing of hypotheses related to clinical issues. To validate the finite element model, an experimental setup was specifically developed and applied on 8 cadaveric tibias. A non-cemente...

Background: Receptor activator of nuclear factor kappa B ligand (RANKL) is one of the key cytokines in the induction of osteoclastogenesis both in vitro and in vivo.Several reports indicated the presence of sRANKL in gingival crevicular fluid of patients with periodontal diseases. Objective: To determine the presence of RANKL in peri-implant crevicular fluid samples of implants with peri-implan...

Objective(S): Implant-related infections are disastrous complications in the clinic. One recent strategy to reduce the rate of infection is using the bioactive coating with an antibiotic. The purpose of these bioactive surfaces is to prevent bacterial adhesion to the implant and, consequently, the development of biofilm. In this study, vancomycin-loaded polymeric coating on imp...

To improve well-known titanium implants, pores can be used for increasing bone formation and close bone-implant interface. Selective Laser Melting (SLM) enables the production of any geometry and was used for implant production with 250-µm pore size. The used pore size supports vessel ingrowth, as bone formation is strongly dependent on fast vascularization. Additionally, proangiogenic factors ...