Objectives: Older people are more prone to chronic diseases and being treated than other age groups; as a result, they use drugs that may be inappropriate lead adverse drug reactions. This study aimed determine the rate of using Beers criterion among elderly in Amirkola City. Methods & Materials: The current descriptive-analytical is part comprehensive plan "Study health status City” AHAP" ...

Objectives Our goal was to assess the association between potentially inappropriate medication use and risk of falls in the Parkinson's disease population. Methods This was a retrospective cohort study conducted at an outpatient Parkinson's Disease Treatment Center. Individuals 65 years of age or older, diagnosed with Parkinson's disease who attended at least three visits in 2015 for physical...

BACKGROUND This study compared individuals whose clinical diagnosis of Alzheimer's disease (AD) matched or did not match neuropathologic results at autopsy on clinical and functional outcomes (cognitive impairment, functional status and neuropsychiatric symptoms). The study also assessed the extent of potentially inappropriate medication use (using potentially unnecessary medications or potenti...

Accounting for subject nonadherence and eliminating inappropriate subjects in clinical trials are critical elements of a successful study. Nonadherence can increase variance, lower study power, and reduce the magnitude of treatment effects. Inappropriate subjects (including those who do not have the illness under study, fail to report exclusionary conditions, falsely report medication adherence...

BACKGROUND Comorbidity and polypharmacy, more prevalent among older persons, may impact the treatment of patients with inflammatory bowel disease (IBD). The aims of this study were to assess the frequency of polypharmacy and medication interactions within a cohort of older patients with IBD and describe IBD treatment patterns. METHODS Cohort study of 190 patients with IBD 65 years or older fo...

We evaluated the evocative effects of four conditions (high- and low-preference activities, low and divided attention) and stimulant medication on the behavior of a 16-year-old boy with attention deficit hyperactivity disorder and moderate mental retardation. All behavior (activity engagement, activity changes, inappropriate touching, rude behaviors, and physical aggression) improved with stimu...

The inappropriate and over-prescribing of medication is an area of nursing fraught with legal and ethical considerations. It can lead to people being chemically restrained and must only be used in exceptional situations. Therapeutic alternatives should take precedent. This article reviews studies on chemical restraint that show high levels of neuroleptic drug prescribing, including pro re nata ...