Water bodies have been severely degraded in recent years due to the indiscriminate use of agro-allied chemicals. The study assesses chemical pollution on surface water quality River Lamurde and Mayo Gwoi. samples were collected from twenty-one (21) sample locations along Mayo-Gwoi determine seasonal variation during wet dry seasons through field determination laboratory-based analysis at Taraba...

Two different devices show that delivery of cancer drugs directly into tumors in vivo can indicate cancer sensitivity; if implemented in clinical practice, these devices have the potential to reduce indiscriminate drug use, to improve survival, and to reduce unnecessary adverse effects (Jonas et al. and Klinghoffer et al., this issue).

To determine the predominant staphylococcal cassette chromosome (SCC) mec element in methicillin-resistant Staphylococcus aureus, we typed 190 isolates from a hospital in Taiwan. We found a shift from type IV to type III SCCmec element during 1992-2003, perhaps caused by selective pressure from indiscriminate use of antimicrobial drugs.

Since the work by Miller, Amon, and Reinhardt, which correctly warned against the indiscriminate adjustment of the maximum step size during Monte Carlo (MC) simulations, some researchers have believed that adjusting the maximum step size always leads to systematic errors. In this paper, I demonstrate that when periodic adjustments are done properly, they can improve the overall accuracy of simu...

Since the initial revelations of pervasive surveillance in 2013, several classes of attacks on Internet communications have been discovered. In this document, we develop a threat model that describes these attacks on Internet confidentiality. We assume an attacker that is interested in undetected, indiscriminate eavesdropping. The threat model is based on published, verified attacks.

The implications of the causal and ubiquitous use, by doctors health-workers and politicians, of the word 'patient' are here discussed. Given that the many implications of this noun do not include health or normality (rather the contrary), it is questionable who, if anyone, profits from its indiscriminate use--and its use, even, at all.

Exosomes and proteasomes are macromolecular complexes that posttranscriptionally regulate gene expression by degrading mRNAs and proteins, respectively. Although the two complexes act on different substrates and are composed of different subunits, they share a similar barrel-like architecture that appears to have evolved to restrict substrate access and prevent indiscriminate degradation.