Objectives. We evaluated immunisation with Bacille Calmette-Guérin (BCG) among newborns in 2011 in the Maringue District, Sofala Province, Mozambique, which includes seven health units. The study was motivated by the fact that in official reports, immunisation coverage was unreliable (more than 100%). Methods. The office of maternal-child health of the central Maringué-Sede health unit provided...

BACKGROUND With the expanded availability of next generation sequencing (NGS)-based clinical genetic tests, clinicians seeking to test patients with Mendelian diseases must weigh the superior coverage of targeted gene panels with the greater number of genes included in whole exome sequencing (WES) when considering their first-tier testing approach. Here, we use an in silico analysis to predict ...

By combining news coverage and survey data from the BP oil spill of 2010, this study demonstrates how the media played an important role in connecting the disaster to President Obama. Rather than criticizing Obama from the outset, the spill reporting escalated from a period of event-based, factual coverage to a highly politicized phase of governmental blame attribution. We utilize a natural exp...

—Many of the WLAN hotspots are significant in size and achieving good coverage may be challenging. The current standard for providing coverage is to distribute individual WLAN access points in the target area. Due to the fact that the in-building environment has many challenges, such as walls and elevators, the number of access points needed by using this method may become significant. There ar...

WSN coverage optimization is an important problem. Considering that the artificial fish algorithm is easy to fall into local optimum and of slow convergence, an improved algorithm has been proposed in this paper. The chaos strategy is used to carry out the initialization of the foraging behavior, which makes the fish swarm evenly distributed in space, to avoid the randomness of the initialized ...

We present a novel set of methods for analyzing coverage properties in dynamic sensor networks. The dynamic sensor network under consideration is studied through a series of snapshots, and is represented by a sequence of simplicial complexes, built from the communication graph at each time point. A method from computational topology called zigzag persistent homology takes this sequence of simpl...

The number of structures of protein-protein complexes deposited to the Protein Data Bank is growing rapidly. These structures embed important information for predicting structures of new protein complexes. This motivated us to develop the PPISP method for predicting interface residues in protein-protein complexes. In PPISP, sequence profiles and solvent accessibility of spatially neighboring su...

With the increasing focus of genetic association on the identification of trait-associated rare variants through sequencing, it is important to identify the most cost-effective sequencing strategies for these studies. Deep sequencing will accurately detect and genotype the most rare variants per individual, but may limit sample size. Low pass sequencing will miss some variants in each individua...

BACKGROUND The Affordable Care Act (ACA) expands Medicaid's tobacco dependence treatment (TDT) coverage; however, these expansions differ in comprehensiveness based on Medicaid eligibility category. PURPOSE To examine whether more generous Medicaid TDT coverage (in terms of cost-sharing requirements and treatments covered) is associated with greater likelihood of quit attempts and successful ...

Area coverage problem in Directional Sensor Networks (DSNs) presents great research challenges including minimization of number of active sensors and overlapping sensing coverage area among them, determination of their active sensing directions in an energy-efficient way, etc. Existing solutions permit to execute coverage enhancement algorithms at each individual sensor nodes, leading to high c...