نتایج جستجو برای: induced osteoporosis
تعداد نتایج: 1001986 فیلتر نتایج به سال:
Drug-induced osteoporosis is common and has a significant impact on the prognosis of patients suffering from chronic debilitating diseases. Glucocorticoids are the drugs causing osteoporotic fractures most frequently, but osteoporosis with fractures is observed also in women treated with aromatase inhibitors for breast cancer, in men receiving anti-androgen therapy for prostate cancer, in postm...
The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.
Background and Aim: Cessation of ovarian function is a major cause postmenopausal osteoporosis. Ovariectomized rats dogs have been used extensively in osteoporosis models. This study examined the effect Pueraria Radix isoflavone extract not only on Bone Mineral Density (BMD) but also bone strength using formation resorption markers ovariectomized as an model. Methods: The model (OVX) induced by...
Osteoclasts play an important role in diseases involving bone loss. In this study, we assessed the effect of a plant-derived natural alkaloid (lycorine, or LY) on osteoclastogenesis in vitro and in vivo. Our in vitro study showed that receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis could be inhibited by LY; this effect was due to inhibition of mitogen-activated...
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