A histochemical study was made of 13 cases of lipidoses of the central nervous system. Niemann-Pick's disease can be differentiated from other cerebral lipidoses by the finding that all affected cells store histochemically stainable phospholipids. Evidence has been adduced indicating that the material stored in infantile amaurotic idiocy is a complex containing ganglioside, cholesterol, and pos...

Until recently the situation in relation to childhood psychoses was extremely confused. There was little agreement among authors about terminology and a general uncertainty about their nature and aetiology. Masterly reviews by Eisenberg' 2 in the United States and Rutter' in the United Kingdom have brought some order to this complex field. Perhaps the most important contribution was the introdu...

We report the case of a five-year-old girl, presenting with difficult-to-treat, symptomatic focal epilepsy, who developed status gelasticus following the introduction of levetiracetam as add-on treatment to oxcarbazepine and diazepam. Gelastic seizures were documented by video-EEG and were responsive to i.v. administration of diazepam. A possible causative role of levetiracetam is suggested. Sp...

Patients in general practice complaining of insomnia of recent origin have been studied in order to ascertain which factors may be of value in the detection of those more susceptible to drug dependence. The type of sleep disturbance was found to be of importance and a personal disturbance scale was found useful as a screening test in two-thirds of the patients. No difference was found in the de...

Astemizole and terfenadine, two potent non-sedative H1 antihistamines, had no effect on itch measured objectively as nocturnal scratching and subjectively on a 10 cm line. Trimeprazine, however, a more sedative but less potent H1 antihistamine, was antipruritic, as was nitrazepam, a sedative benzodiazepine. We concluded (a) that antipruritic drugs act centrally by a property related to sedation...

a 29 days old pakistani female infant was presented to our outpatient department with two weeks history of a rapidly progressing large size facial hemangioma involving most of the right cheek and right eyelids. the infant was unable to open the right eye. there was also a small hemangioma on the right second toe. additionally, three similar lesions were found on the right side of the palate and...

parents who have a baby with infantile colic experienced a different thought and emotions such as hopelessness, fatigue and impasses. in this study, our living experience as a professional nursing parents' are represented with new relieving modality for infantile colic. herein, we report a new relieving dietary protocol for a colicky infant with non- immunoglobulin e – mediated protein ind...

Hemangiopericytoma is a rare vascular tumor observed mostly in adults. It usually presents with a painless slowly enlarging mass. The infantile type with much rarer occurrence has a different course compared to adults. Very few case reports have been described in the literature with disease onset in the infancy. The first reported case of infantile hemangiopericytoma of limbs from the Middle ...