SEVERE or intractable chest pain, associated with sweating, vomiting, precipitate fall of arterial blood pressure, fever, and evidence of shock or collapse, clearly indicates a diagnosis of acute myocardial infaretion. In marked contrast is the entity of angina pectoris, with its paroxysms of chest pain after effort, typical radiation of pain into the arm, feeling of viselike constriction in th...

SEVERE or intractable chest pain, associated with sweating, vomiting, precipitate fall of arterial blood pressure, fever, and evidence of shock or collapse, clearly indicates a diagnosis of acute myocardial infaretion. In marked contrast is the entity of angina pectoris, with its paroxysms of chest pain after effort, typical radiation of pain into the arm, feeling of viselike constriction in th...

OBJECTIVES We undertook this study to assess the relationship between presentation pattern and mortality in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention. METHODS This registry included 10,455 patients with ACS, of whom 2,853 patients had ST-segment elevation myocardial infarction(STEMI), 3,060 patients had non-ST-segment elevation myocardial infarc...

BACKGROUND The extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated. METHODS AND RESULTS Included were outpatients with established coronary artery disease who were enrolled in the REACH registry and were followed for 4 years. Angina at baseline was defined as necessitating episodic or permanent antianginal treat...

STUDY OBJECTIVE To test the hypothesis that the active coronary endothelial lesions in unstable angina raise the endothelin concentration in coronary venous blood. DESIGN Systemic and coronary venous blood samples were obtained from unselected patients with the clinical syndromes of either stable or unstable angina at the time of cardiac catheterisation and coronary arteriography. Control ven...

SEVERE or intractable chest pain, associated with sweating, vomiting, precipitate fall of arterial blood pressure, fever, and evidence of shock or collapse, clearly indicates a diagnosis of acute myocardial infaretion. In marked contrast is the entity of angina pectoris, with its paroxysms of chest pain after effort, typical radiation of pain into the arm, feeling of viselike constriction in th...

BACKGROUND Discharging patients with acute myocardial infarction or unstable angina from the emergency department because of missed diagnoses can have dire consequences. We studied the incidence of, factors related to, and clinical outcomes of failure to hospitalize patients with acute cardiac ischemia. METHODS We analyzed clinical data from a multicenter, prospective clinical trial of all pa...

We got data from the Scottish morbidity record for Scottish residents aged at least 18 years with a “first” emergency hospitalisation for myocardial infarction (codes ICD-9 (international classification of diseases, ninth revision) 410, ICD-10 I21 or I22), angina (ICD-9 411 or 413; ICD-10 I20 or I24.9) or “other chest pain” (ICD-9 786.5; ICD-10 R07), between 1990 and 2000. We analysed discharge...

OBJECTIVE To assess the effects of calcium channel blockers on development of infarcts, reinfarction, and mortality. DESIGN A systematic overview of all randomised trials of calcium channel blockers in myocardial infarction and unstable angina. PATIENTS 19,000 Patients in 28 randomised trials. RESULTS In the trials of myocardial infarction 873 deaths occurred among 8870 patients randomise...

Coronary artery spasm, marked by coronary vasoconstriction, is one of the etiologies myocardial ischemia, often presenting as vasospastic angina. Vasospastic angina diagnosed when which predominantly occurs at rest, accompanied ST-segment changes in ECG, or setting borderline ECG changes, a positive provocation test through angiography required. Although spasms could manifest wide clinical sett...