We report the successful treatment of infective endocarditis caused by Streptococcus mitis with linezolid in a patient with pre-existing valvular heart disease. The patient had multiple allergies to conventional antibiotics. Linezolid may provide an oral alternative in the treatment of infective endocarditis in patients with adverse drug reactions to traditional antibiotic regimens.

BACKGROUND Infective endocarditis is associated with not only cardiac complications but also neurologic, renal, musculoskeletal, and systemic complications related to the infection, such as embolization, metastatic infection, and mycotic aneurysm. CASE PRESENTATION We report three cases (the first patient is Chinese and the other two are Koreans) of complicated infective endocarditis; two of ...

Infective endocarditis remains a major cause of morbidity and mortality in the U.S., with an estimated number of 10–15,000 new cases being diagnosed each year (1). Although the number of cases of infective endocarditis occurring as a result of rheumatic disease is diminishing, this reduction in cases has been replaced by an increased incidence of endocarditis among intravenous drug users and ol...

BACKGROUND Sub-acute left-sided bacterial endocarditis is a serious condition that may present with variable clinical manifestations. Its symptoms include both sterile and infected emboli, and various immunological phenomena. CASE REPORT This report presents a 55 year old man with frequency and dysuria after a lithotripsy and several admissions with urosepsis. Due to the suspicion of infectiv...

Several large series of cases of infective endocarditis have mentioned the paucity of pulmonic valve involvement. 1-3 A recent study by Hubbell et a14 found no cases of pulmonic valve endocarditis in a group of 79 drug addicts with 97 separate episodes of infective endocarditis. It is possible that the paucity of such reports may be due in part to the difficulty of assessing the pulmonic valve....

Infective endocarditis is a common clinical problem in industrialized countries. Risk factors include abnormal cardiac valves, a history of endocarditis, intracardiac devices, prosthetic valves and intravenous drug use. We report a case of polymicrobial infective endocarditis in a 33 year-old female with a history chronic heroin use caused by Neisseria sicca and Haemophilus parainfluenzae. We b...

Felty syndrome is a rare seropositive rheumatoid arthritis (RA), splenomegaly, and absolute neutropenia [1] occurring in less than 1% of patients with RA [2]. As the disease itself asymptomatic, usually present acute infection superimposed on long-standing, erosive diagnosis Infective endocarditis one most common life-threatening infectious syndromes We describe case infective patient syndrome.

Streptococcus species are important causes of infective endocarditis but species identification remains challenging. We report two cases of infective endocarditis due to Streptococcus tigurinus-like organisms, which were first identified by 16S ribosomal RNA gene sequence analysis and subsequently confirmed using phylogeny based on the analysis of the shetA gene encoding exfoliative toxin.

Here we describe a case of infective endocarditis caused by Tropheryma whipplei in a patient with no other symptoms of Whipple's disease. The case was diagnosed using broad-range PCR and confirmed by specific PCRs. We review the cases of infective endocarditis presenting as the only manifestation of Whipple's disease reported in the literature.

Repeat infective endocarditis due to the same species can represent relapse of the initial infection or a new infection. We used time-based clinical criteria and pulsed-field gel electrophoresis-based molecular criteria to classify 13 cases of repeat infective endocarditis as either relapse or reinfection. The agreement between clinical and molecular criteria was imperfect (agreement in 10 [77%...