Inflammation is defined as the local response of living mammalian tissues to injury due to any agent. Inflammation involves 2 basic processes early inflammatory response later followed by healing. There are two types of inflammation, Acute and Chronic. Acute inflammation is of short duration and represents the early body reaction, resolves quickly and is usually followed by healing. Chronic inf...

BACKGROUND Protective host responses to respiratory pathogens are typically characterized by inflammation. However, lung inflammation is not always protective and it may even become deleterious to the host. We have recently reported substantial protection against Streptococcus pneumoniae (pneumococcal) pneumonia by induction of a robust inflammatory innate immune response to an inhaled bacteria...

diabetes mellitus is a chronic disease which affects the healing ability of the pulp and periodontium. the aim of the present study was to assess the histopathologic response of dental pulp to pulp capping using mta or cem cement in diabetic rats. thirty two wistar male rats aged between 8 and 10 weeks (weight: 200-250g) were divided into two groups of diabetic (n=16) and healthy (n=16) animals...

While extensive studies report that neonatal hypoxia-ischemia (HI) induces long-term cognitive impairment via inflammatory responses in the brain, little is known about the role of early peripheral inflammation response in HI injury. Here we used a neonatal hypoxia rodent model by subjecting postnatal day 0 (P0d) rat pups to systemic hypoxia (3.5 h), a condition that is commonly seen in clinic ...

Oral microbes play a critical role in maintaining oral homeostasis. Microbial dysbiosis promotes disease pathogenesis through several mechanisms. Recent studies have revealed that microbial imbalance and sustained inflammation are involved progression. The adverse interaction triggered by host immune response to microorganisms can lead systemic diseases. Here, we reviewed how communicate with h...

Inflammation is the process by which immune system recognizes and removes environmental factors, begins healing process. can be either acute or chronic. However, cause of many chronic inflammatory conditions poorly understood. Chronic responses are an ongoing as long factor present. Sometimes, response makes body attack itself. In this paper a closer look at finding out causes inflammations, ho...

Neuroinflammation is a prominent feature of the response to CNS trauma. It also an important hallmark various neurodegenerative diseases in which inflammation contributes progression pathology. Inflammation can contribute secondary damage and therefore excellent therapeutic target for range neurological conditions. nervous system complex varies its fine details different involves wide variety s...

background: inverse relationship between helminths infection and immune-mediated diseases has inspired researchers to investigate therapeutic potential of helminths in allergic asthma. helminth unique ability to induce immunoregulatory responses has already been documented in several experimental studies. this study was designed to investigate whether excretory/secretory (es) and somatic produc...

spinal cord injury (sci) as a destructive crash result in neurons degeneration. the sci lead to the onset of biochemical and molecular cascades such as inflammation that in turn has a key role in neurodegeneration development. the previous studies demonstrated the role of tnf-α and inos genes in intensifying the process after sci. as a consequence, these genes overexpression intensify the infla...