A milk membrane glycoprotein, MFG-E8 [milk fat globule-EGF (epidermal growth factor) factor 8], is expressed abundantly in lactating mammary glands in stage- and tissue-specific manners, and has been believed to be secreted in association with milk fat globules. In the present paper, we describe further up-regulation of MFG-E8 in involuting mammary glands, where the glands undergo a substantial...

It has recently been shown, in experiments on lactating rats with hypothalamic lesions, that milk can be expressed from the mammary glands of rearing-failed, lesioned rats by weak palpation even 10 days after the operation when vigorous suckling by young continued, and that a considerable amount of milk is obtained from mammary glands of these lesioned rats by the regular administration of oxyt...

HASHIMOTO (1912) remarked on the similarity of the form of thyroiditis, described by him and now known by his name, to the lesions of Mikulicz's disease, which include a chronic inflammatory reaction in the lacrimal glands. Only recently, however, has evidence accumulated of a true association between non-infective chronic inflammatory lesions of the thyroid and lacrimal glands (Anderson, Gray,...

Small ruminant lentiviruses (SRLV) are members of the Retrovirus family comprising the closely related Visna/Maedi Virus (VMV) and the Caprine Arthritis-Encephalitis Virus (CAEV), which infect sheep and goats. Both infect cells of the monocyte/macrophage lineage and cause lifelong infections. Infection by VMV and CAEV can lead to Visna/Maedi (VM) and Caprine Arthritis-Encephalitis (CAE) respect...

I . Stages are described in the development of the mammae of male rabbits responding to regular injections of oestrogen and progesterone. 2. It is suggested that the extra mammary lobes which develop under this treatment are derived from hair follicles and sebaceous glands by the loss of the hairs from the follicles and the proliferation of sebaceous glands and ducts. 3. This may throw light on...

background there are few reports from iran about the epidemiology and clinical features of inflammatory bowel disease (ibd). this study aims to determine the epide­miologic profile and clinical features of ibd in northwest iran referral centers. methods in a cross-sectional setting, we evaluated 200 patients with definitive diagno­ses of ibd who referred to tabriz educational hospitals during t...

The histological study was carried out on mammary glands collected from 14 Madras red sheep, 7 in lactating period 7 in non-lactation period. The connective tissue became reduced and lobuloalveolar tissue was predominantly increased during lactating period. The alveoli were laminated, filled with secretion and lined by cuboidal active secretory cells containing lipid droplets and protein granul...

Milk samples were taken from rats feeding ten pups and from both the suckled and non-suckled glands of rats feeding two pups. The lipid, protein and lactose concentrations were similar in the milks from the secreting glands, but the fluid from the non-suckled glands contained less lactose and lipid but significantly higher total protein and transferrin concentrations. The fatty acid composition...