The study was conducted in 60, ASA grade I & II patients for BIS guided sedation during middle ear surgery under local anesthesia. All patients were Pre medicated with Inj. Fentanyl 2μgm/kg and Glycopyrolate 5μg/kg, 10 minutes before surgery. Local anesthesia was given by the experienced ENT surgeon using lidocaine 2% with adrenaline 1:200,000. Patients were randomly divided into two groups. Gr...

With new guidelines for the control of heparin infusion rates the proportion of kaolin cephalin clotting time ratios was significantly improved compared with ratios achieved without their use. Further improvement might result from careful preparation and delivery of the infusion.

Patients with idiopathic normal pressure hydrocephalus (INPH) have a disturbance in the cerebrospinal fluid (CSF) system. The treatment is neurosurgical – a shunt is placed in the CSF system. The infusion test is used to assess CSF system dynamics and to aid in the selection of patients that will benefit from shunt surgery. The infusion test can be divided into three parts: a mathematical model...

We have had this study to evaluate the clinical profile of target-controlled infusion-based anesthesia using remifentanil and propofol. 116 ASA I-II patients undergoing elective laparoscopic cholecystectomy (LCH) were enrolled. TCI Remifentanil was set at 8 micrograms. L - 1 as target and TCI propofol at 4 mcg/ml throughout the whole procedure. The hemodynamics during induction of anesthesia an...

The effects of infusion of normal saline (NS) and glucose-insulin-potassium (GIK) with either low or high G concentrations on hemodynamics and exercise tolerance were studied in patients with angina pectoris. Studies were performed at rest and during exercise, twice before and once after one of the infusions. Eleven patients (low-G GIK group) received 150 ml of GIK solution that contained 15 g ...

The effects of infusion of normal saline (NS) and glucose-insulin-potassium (GIK) with either low or high G concentrations on hemodynamics and exercise tolerance were studied in patients with angina pectoris. Studies were performed at rest and during exercise, twice before and once after one of the infusions. Eleven patients (low-G GIK group) received 150 ml of GIK solution that contained 15 g ...

In order to clarify the relative contribution of the liver to the short term disposition of propofol, hepatic blood flow was measured during induction of anaesthesia with an i.v. bolus dose of propofol 2 mg kg-1. Total clearance of the drug was 2390 (SD 340) ml min-1, hepatic extraction 82% and hepatic clearance 1060 (260) ml min-1. During the 60-min period of observation, hepatic extraction of...

Introduction Vancomycin hydrochloride is an antimicrobial commonly used and studied in the treatment of patient with healthcare-associated infections. However, there are few studies related to this drug stability during administration. In intensive care units, mainly pediatric and neonatal, the clinical conditions and specific needs of patients may require longer time of vancomycin hydrochlorid...

      The aim of this study was to investigate the prevalence of Mg deficiency and effect of aminophylline infusion on urine magnesium concentration after magnesium loading test (MLT). To determine serum Mg, venous blood specimens were obtained just before the first MLT. Two MLTs were performed. The first one was done before starting aminophylline infusion and the 2nd one was done du...